CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045010
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Keratin, type I cytoskeletal 19 
Protein Synonyms/Alias
  
Gene Name
 KRT19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71APGTDLAKILSDMRSubiquitination[1, 2]
89VMAEQNRKDAEAWFTubiquitination[1, 2]
141LQSQLSMKAALEDTLubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 181 AA 
Protein Sequence
MSVEADINGL RRVLDELTLA RTDLEMQIEG LKEELAYLKK NHEEEISTLR GQVGGQVSVE 60
VDSAPGTDLA KILSDMRSQY EVMAEQNRKD AEAWFTSRTE ELNREVAGHT EQLQMSRSEV 120
TDLRRTLQGL EIELQSQLSM KAALEDTLAE TEARFGAQLA HIQALISGIE AQLGDVRADS 180
E 181 
Gene Ontology
 GO:0016010; C:dystrophin-associated glycoprotein complex; IEA:Compara.
 GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
 GO:0042383; C:sarcolemma; IEA:Compara.
 GO:0030018; C:Z disc; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0060706; P:cell differentiation involved in embryonic placenta development; IEA:Compara. 
Interpro
 IPR016044; F.
 IPR001664; IF.
 IPR002957; Keratin_I.
 IPR009053; Prefoldin. 
Pfam
 PF00038; Filament 
SMART
  
PROSITE
  
PRINTS
 PR01248; TYPE1KERATIN.