CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043067
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Alpha-mannosidase 2x 
Protein Synonyms/Alias
  
Gene Name
 MAN2A2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
58ICCQFDFKRLPGGRIubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 793 AA 
Protein Sequence
YAIKKHFAAT HSLEFMWRQT WDSDSSTDIF CHMMPFYSYD VPHTCGPDPK ICCQFDFKRL 60
PGGRINCPWK VPPRAITEAN VAERAALLLD QYRKKSQLFR SNVLLVPLGD DFRYDKPQEW 120
DAQFFNYQRL FDFFNSRPNL HVQDHYWTGY YTSRPFYKSL DRVLEAHLRG AEVLYSLAAA 180
HARRSGLAGR YPLSDFTLLT EARRTLGLFQ HHDAITGTAK EAVVVDYGVR LLRSLVNLKQ 240
VIIHAAHYLV LGDKETYHFD PEAPFLQVDD TRLSHDALPE RTVIQLDSSP RFVVLFNPLE 300
QERFSMVSLL VNSPRVRVLS EEGQPLAVQI SAHWSSATEA VPDVYQVSVP VRLPALGLGV 360
LQLQLGLDGH RTLPSSVRIY LHGRQLSVSR HEAFPLRVID SGTSDFALSN RYMQVWFSGL 420
TGLLKSIRRV DEEHEQQVDM QVLVYGTRTS KDKSGAYLFL PDGEAKPYVP KEPPVLRVTE 480
GPFFSEVVAY YEHIHQAVRL YNLPGVEGLS LDISSLVDIR DYVNKELALH IHTDIDSQGI 540
FFTDLNGFQV QPRRYLKKLP LQANFYPMPV MAYIQDAQKR LTLHTAQALG VSSLKDGQLE 600
VILDRRLMQD DNRGLGQGLK DNKRTCNRFR LLLERRTVGS EVQDSHSTSY PSLLSHLTSM 660
YLNAPALALP VARMQLPGPG LRSFHPLASS LPCDFHLLNL RTLQAEEDTL PSAETALILH 720
RKGFDCGLEA KNLGFNCTTS QGKVALGSLF HGLDVVFLQP TSLTLLYPLA SPSNSTDVYL 780
EPMEIATFRL RLG 793 
Gene Ontology
 GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006013; P:mannose metabolic process; IEA:InterPro. 
Interpro
 IPR011013; Gal_mutarotase_SF_dom.
 IPR011330; Glyco_hydro/deAcase_b/a-brl.
 IPR013780; Glyco_hydro_13_b.
 IPR027291; Glyco_hydro_38/57_N.
 IPR011682; Glyco_hydro_38_C.
 IPR015341; Glyco_hydro_38_cen_dom.
 IPR000602; Glyco_hydro_38_N. 
Pfam
 PF09261; Alpha-mann_mid
 PF01074; Glyco_hydro_38
 PF07748; Glyco_hydro_38C 
SMART
 SM00872; Alpha-mann_mid 
PROSITE
  
PRINTS