UniProt Accession

 THYN1_HUMAN; Q9P016; Q567Q2; Q9H3L4; Q9HC20 

Genbank Protein ID

 AF087886; AF059619; AF182413; AF161493; BC006978; BC093074 

Genbank Nucleotide ID

 AAP97185.1; AAG43118.1; AAG14949.1; AAF29108.1; AAH06978.1; AAH93074.1 

Protein Name

 Thymocyte nuclear protein 1 

Protein Synonyms/Alias

 Thymocyte protein Thy28 

Gene Name

 THYN1 

Gene Synonyms/Alias

 THY28; HSPC144; MDS012; My0054 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
16	AGTSGSDKGLSGKRT	acetylation	[1]
42	VEDSNPQKTSATKNC	ubiquitination	[1]
51	SATKNCLKNLSSHWL	acetylation	[1]
60	LSSHWLMKSEPESRL	ubiquitination	[1, 2]
69	EPESRLEKGVDVKFS	ubiquitination	[1, 2]
81	KFSIEDLKAQPKQTT	acetylation	[3]
81	KFSIEDLKAQPKQTT	ubiquitination	[1, 2]
85	EDLKAQPKQTTCWDG	ubiquitination	[1, 2, 4]
119	FFYHSNCKEPGIAGL	ubiquitination	[1, 2]
131	AGLMKIVKEAYPDHT	ubiquitination	[2]
142	PDHTQFEKNNPHYDP	ubiquitination	[1]
152	PHYDPSSKEDNPKWS	ubiquitination	[2]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [4] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

 MOTIF 5 10 Nuclear localization signal (By  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 225 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; ISS:HGNC. 

Interpro

 IPR002740; EVE_domain.
 IPR015947; PUA-like_domain. 

Pfam

 PF01878; EVE 

SMART

  

PROSITE

  

PRINTS