CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019405
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BTB/POZ domain-containing protein 6 
Protein Synonyms/Alias
 Lens BTB domain protein 
Gene Name
 BTBD6 
Gene Synonyms/Alias
 BDPL 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
329RLDFPLTKRKGLAPQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Adapter protein for the CUL3 E3 ubiquitin-protein ligase complex. Involved in late neuronal development and muscle formation (By similarity). 
Sequence Annotation
 DOMAIN 83 153 BTB.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 485 AA 
Protein Sequence
MAAELYAPAS AAAADLANSN AGAAVGRKAG PRSPPSAPAP APPPPAPAPP TLGNNHQESP 60
GWRCCRPTLR ERNALMFNNE LMADVHFVVG PPGATRTVPA HKYVLAVGSS VFYAMFYGDL 120
AEVKSEIHIP DVEPAAFLIL LKYMYSDEID LEADTVLATL YAAKKYIVPA LAKACVNFLE 180
TSLEAKNACV LLSQSRLFEE PELTQRCWEV IDAQAEMALR SEGFCEIDRQ TLEIIVTREA 240
LNTKEAVVFE AVLNWAEAEC KRQGLPITPR NKRHVLGRAL YLVRIPTMTL EEFANGAAQS 300
DILTLEETHS IFLWYTATNK PRLDFPLTKR KGLAPQRCHR FQSSAYRSNQ WRYRGRCDSI 360
QFAVDRRVFI AGLGLYGSSS GKAEYSVKIE LKRLGVVLAQ NLTKFMSDGS SNTFPVWFEH 420
PVQVEQDTFY TASAVLDGSE LSYFGQEGMT EVQCGKVAFQ FQCSSDSTNG TGVQGGQIPE 480
LIFYA 485 
Gene Ontology
 GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. 
Interpro
 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR012983; PHR. 
Pfam
 PF07707; BACK
 PF00651; BTB
 PF08005; PHR 
SMART
 SM00875; BACK
 SM00225; BTB 
PROSITE
 PS50097; BTB 
PRINTS