| Tag | Content |
|---|
| CPLM ID | CPLM-021109 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tripartite motif-containing protein 54 |
Protein Synonyms/Alias | Muscle-specific RING finger protein; MuRF; Muscle-specific RING finger protein 3; MuRF-3; MuRF3; RING finger protein 30 |
Gene Name | Trim54 |
Gene Synonyms/Alias | Murf; Rnf30 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 8 | MNFTVGFKPLLGDAH | ubiquitination | [1] | | 49 | CQHNLCRKCANDVFQ | ubiquitination | [1] | | 168 | APLPTIYKRQKSELS | ubiquitination | [1] | | 289 | QAKELINKVGAMSKV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May bind and stabilize microtubules during myotubes formation. |
Sequence Annotation | DOMAIN 271 329 COS.
ZN_FING 26 82 RING-type.
ZN_FING 121 163 B box-type.
REGION 168 211 Mediates microtubule-binding and |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Differentiation; Metal-binding; Microtubule; Reference proteome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 366 AA |
Protein Sequence | MNFTVGFKPL LGDAHNMDNL EKQLICPICL EMFSKPVVIL PCQHNLCRKC ANDVFQASNP 60
LWQSRGSTTV SSGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESSRPLHAKA 120
EQHLMCEEHE DEKINIYCLS CEVPTCSLCK VFGAHKDCEV APLPTIYKRQ KSELSDGIAM 180
LVAGNDRVQA VITQMEEVCQ TIEDNSRRQK QLLNQRFETL CAVLEERKGE LLQALAREQE 240
EKLQRVRGLI RQYGDHLEGS SKLVESAIQS MEEPQMALYL QQAKELINKV GAMSKVELAG 300
RPEPGYESME QFSVSVEHVA EMLRTIDFQP GAAGDEEDDD MALDGEEGNA GLEEERLDVP 360
EGSGLH 366 |
Gene Ontology | GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005875; C:microtubule associated complex; IDA:MGI. GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. GO:0008017; F:microtubule binding; IDA:MGI. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. GO:0007026; P:negative regulation of microtubule depolymerization; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |