| Tag | Content |
|---|
| CPLM ID | CPLM-007735 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional regulator FrlR |
Protein Synonyms/Alias | |
Gene Name | frlR |
Gene Synonyms/Alias | yhfR; b3375; JW5698 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 102 | VSQGKATKEKVIEQE | acetylation | [1] | | 104 | QGKATKEKVIEQERV | acetylation | [1] | | 139 | CRVMYLDKEPLFIDS | acetylation | [1] | | 197 | AATRPQAKWLKCELG | acetylation | [1] | | 200 | RPQAKWLKCELGEPL | acetylation | [1] | | 220 | IAFDQNDKPVHVSEL | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | May regulate the transcription of the frlABCD operon. |
Sequence Annotation | DOMAIN 10 78 HTH gntR-type.
DNA_BIND 38 57 H-T-H motif (Potential). |
Keyword | Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 243 AA |
Protein Sequence | MSATDRYSHQ LLYATVRQRL LDDIAQGVYQ AGQQIPTENE LCTQYNVSRI TIRKAISDLV 60
ADGVLIRWQG KGTFVQSQKV ENALLTVSGF TDFGVSQGKA TKEKVIEQER VSAAPFCEKL 120
NIPGNSEVFH LCRVMYLDKE PLFIDSSWIP LSRYPDFDEI YVEGSSTYQL FQERFDTRVV 180
SDKKTIDIFA ATRPQAKWLK CELGEPLFRI SKIAFDQNDK PVHVSELFCR ANRITLTIDN 240
KRH 243 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |