Tag | Content |
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CPLM ID | CPLM-010002 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glucosyl-3-phosphoglycerate phosphatase |
Protein Synonyms/Alias | GpgP; Mannosyl-3-phosphoglycerate phosphatase; MpgP |
Gene Name | gpgP |
Gene Synonyms/Alias | Rv2419c; MT2492 |
Created Date | July 27, 2013 |
Organism | Mycobacterium tuberculosis |
NCBI Taxa ID | 1773 |
Lysine Modification | Position | Peptide | Type | References |
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47 | AAAEVLGKRQPLLIV | pupylation | [1] |
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Reference | [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] . Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH. PLoS One. 2010 Jan 6;5(1):e8589. [ PMID: 20066036] |
Functional Description | Involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the dephosphorylation of glucosyl-3-phosphoglycerate (GPG) to glucosylglycerate (GG). GPG is the preferred substrate,but a lower activity is measured with mannosyl-3-phosphoglycerate (MPG) and mannosylglucosyl-3-phosphoglycerate (MGPG). |
Sequence Annotation | ACT_SITE 11 11 Tele-phosphohistidine intermediate (By ACT_SITE 159 159 By similarity. CROSSLNK 47 47 Isoglutamyl lysine isopeptide (Lys-Gln) |
Keyword | Complete proteome; Hydrolase; Isopeptide bond; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 223 AA |
Protein Sequence | MRARRLVMLR HGQTDYNVGS RMQGQLDTEL SELGRTQAVA AAEVLGKRQP LLIVSSDLRR 60 AYDTAVKLGE RTGLVVRVDT RLRETHLGDW QGLTHAQIDA DAPGARLAWR EDATWAPHGG 120 ESRVDVAARS RPLVAELVAS EPEWGGADEP DRPVVLVAHG GLIAALSAAL LKLPVANWPA 180 LGGMGNASWT QLSGHWAPGS DFESIRWRLD VWNASAQVSS DVL 223 |
Gene Ontology | GO:0050531; F:mannosyl-3-phosphoglycerate phosphatase activity; IEA:EC. |
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