CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028301
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gephyrin 
Protein Synonyms/Alias
 Gphn protein 
Gene Name
 Gphn 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
101DVTPEATKEVIEREAubiquitination[1]
148IINLPGSKKGSQECFubiquitination[1]
347HSAVDITKVARRHRMubiquitination[1]
681FVVPALRKMQGILDPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 772 AA 
Protein Sequence
MATEGMILTN HDHQIRVGVL TVSDSCFRNL AEDRSGINLK DLVQDPSLLG GTISAYKIVP 60
DEIEEIKETL IDWCDEKELN LILTTGGTGF APRDVTPEAT KEVIEREAPG MALAMLMGSL 120
NVTPLGMLSR PVCGIRGKTL IINLPGSKKG SQECFQFILP ALPHAIDLLR DAIVKVKEVH 180
DELEDLPSPP PPLSPPPTTS PHKQTEDKGV QCEEEEEEKK DSGVASTEDS SSSHITAAAL 240
AAKKHPFYTS PALFMANHGQ PIPGLISYSH HATGSADKRI PDSIISRGVQ VLPRDTASLS 300
TTPSESPRAQ ATSRLSTASC PTPKVQSRCS SKENILRASH SAVDITKVAR RHRMSPFPLT 360
SMDKAFITVL EMTPVLGTEI INYRDGMGRV LAQDVYAKDN LPPFPASVKD GYAVRAADGP 420
GDRFIIGESQ AGEQPTQTVM PGQVMRVTTG APIPCGADAV VQVEDTELIR ESDDGTEELE 480
VRILVQARPG QDIRPIGHDI KRGECVLAKG THMGPSEIGL LATVGVTEVE VNKFPVVAVM 540
STGNELLNPE DDLLPGKIRD SNRSTLLATI QEHGYPTINL GIVGDNPDDL LNALNEGISR 600
ADVIITSGGV SMGEKDYLKQ VLDIDLHAQI HFGRVFMKPG LPTTFATLDI DGVRKIIFAL 660
PGNPVSAVVT CNLFVVPALR KMQGILDPRP TIIKARLSCD VKLDPRPEYH RCILTWHHQE 720
PLPWAQSTGN QMSSRLMSMR SANGLLMLPP KTEQYVELHK GEVVDVMVIG RL 772 
Gene Ontology
 GO:0019897; C:extrinsic to plasma membrane; TAS:MGI.
 GO:0005622; C:intracellular; IDA:MGI.
 GO:0008092; F:cytoskeletal protein binding; TAS:MGI.
 GO:0007529; P:establishment of synaptic specificity at neuromuscular junction; IMP:MGI.
 GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:InterPro. 
Interpro
 IPR020817; Mo_cofactor_synthesis.
 IPR008284; MoCF_biosynth_CS.
 IPR005111; MoeA_C_domain_IV.
 IPR005110; MoeA_linker/N.
 IPR001453; Mopterin-bd_dom. 
Pfam
 PF00994; MoCF_biosynth
 PF03454; MoeA_C
 PF03453; MoeA_N 
SMART
 SM00852; MoCF_biosynth 
PROSITE
 PS01078; MOCF_BIOSYNTHESIS_1
 PS01079; MOCF_BIOSYNTHESIS_2 
PRINTS