CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028752
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 CD44 antigen 
Protein Synonyms/Alias
  
Gene Name
 Cd44 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
753EMVHLVNKEPSETPDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 780 AA 
Protein Sequence
MDKFWWHTAW GLCLLQLSLA HPHQQIDLNV TCRYAGVFHV EKNGRYSISR TEAADLCQAF 60
NSTLPTMDQM KLALSKGFET CRYGFIEGNV VIPRIHPNAI CAANHTGVYI LVTSNTSHYD 120
TYCFNASAPP EEDCTSVTDL PNSFDGPVTI TIVNRDGTRY SKKGEYRTHQ EDIDASNIID 180
DDVSSGSTIE KSTPESYILH TYLPTEQPTG DQDDSFFIRS TLATIASTVH SKSHAAAQKQ 240
NNWIWSWFGN SQSTTQTQEP TTSATTALMT TPETPPKRQE AQNWFSWLFQ PSESKSHLHT 300
TTKMPGTESN TNPTGWEPNE ENEDETDKYP SFSGSGIDDD EDFISSTIAS TPRVSARTED 360
NQDWTQWKPN HSNPEVLLQT TTRMADIDRI STSAHGENWT PEPQPPFNNH EYQDEEETPH 420
ATSTTPNSTA EAAATQQETW FQNGWQGKNP PTPSEDSHVT EGTTASAHNN HPSQRITTQS 480
QEDVSWTDFF DPISHPMGQG HQTESKDTDS SHSTTLQPTA APNTHLVEDL NRTGPLSVTT 540
PQSHSQNFST LHGEPEEDEN HPTTSILPSS TKSGAKDARR GGSLPTDTTT SVEGYTFQYP 600
DTMENGTLFP VTPAKTEVFG ETEVTLATDS NVNVDGSLPG DRDSSKDSRG SSRTVTHGSE 660
LAGHSSANQD SGVTTTSGPM RRPQIPEWLI ILASLLALAL ILAVCIAVNS RRRCGQKKKL 720
VINGGNGTVE DRKPSELNGE ASKSQEMVHL VNKEPSETPD QCMTADETRN LQSVDMKIGV 780 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IDA:MGI.
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0005540; F:hyaluronic acid binding; IDA:MGI.
 GO:0004415; F:hyalurononglucosaminidase activity; IEA:Compara.
 GO:0004888; F:transmembrane signaling receptor activity; IEA:Compara.
 GO:0060442; P:branching involved in prostate gland morphogenesis; IMP:MGI.
 GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:MGI.
 GO:0051216; P:cartilage development; IEA:Compara.
 GO:0007155; P:cell adhesion; IDA:MGI.
 GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Compara.
 GO:0030214; P:hyaluronan catabolic process; IEA:Compara.
 GO:0070487; P:monocyte aggregation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IEA:Compara.
 GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Compara.
 GO:0010628; P:positive regulation of gene expression; IGI:MGI.
 GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IEA:Compara.
 GO:1900625; P:positive regulation of monocyte aggregation; IEA:Compara.
 GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Compara.
 GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0016055; P:Wnt receptor signaling pathway; IDA:MGI.
 GO:0002246; P:wound healing involved in inflammatory response; IMP:MGI. 
Interpro
 IPR016186; C-type_lectin-like.
 IPR016187; C-type_lectin_fold.
 IPR001231; CD44_antigen.
 IPR000538; Link. 
Pfam
 PF00193; Xlink 
SMART
 SM00445; LINK 
PROSITE
 PS01241; LINK_1
 PS50963; LINK_2 
PRINTS
 PR00658; CD44.
 PR01265; LINKMODULE.