UniProt Accession

 B4DP80_HUMAN; B4DP80 

Genbank Protein ID

 AK298222 

Genbank Nucleotide ID

 BAG60492.1 

Protein Name

 NAD(P)H-hydrate epimerase 

Protein Synonyms/Alias

 Apolipoprotein A-I-binding protein; NAD(P)HX epimerase 

Gene Name

 APOA1BP 

Gene Synonyms/Alias

 AIBP 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
151	LVCARHLKLFGYEPT	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity). 

Sequence Annotation

 DOMAIN 84 294 YjeF N-terminal (By similarity).
 REGION 138 142 NAD(P)HX (By similarity).
 REGION 208 214 NAD(P)HX (By similarity).
 METAL 139 139 Potassium (By similarity).
 METAL 204 204 Potassium (By similarity).
 METAL 240 240 Potassium (By similarity).
 BINDING 237 237 NAD(P)HX (By similarity).  

Keyword

 Isomerase; Lipoprotein; Metal-binding; Mitochondrion; NAD; Nucleotide-binding; Potassium; Secreted; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 307 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0052856; F:NADHX epimerase activity; IEA:HAMAP.
 GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. 

Interpro

 IPR026600; NnrE/AIBP.
 IPR004443; YjeF_N_dom. 

Pfam

 PF03853; YjeF_N 

SMART

  

PROSITE

 PS51385; YJEF_N 

PRINTS