CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028010
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LD46328p 
Protein Synonyms/Alias
 Syndapin 
Gene Name
 Synd 
Gene Synonyms/Alias
 syndapin; CG33094; Dmel_CG33094 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
137KDLEDLFKKAQKPWAacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
 METAL 69 69 Sodium; via carbonyl oxygen.
 METAL 70 70 Sodium; via carbonyl oxygen.
 METAL 72 72 Sodium; via carbonyl oxygen.
 METAL 74 74 Sodium; via carbonyl oxygen.
 METAL 79 79 Sodium.  
Keyword
 3D-structure; Complete proteome; Metal-binding; Reference proteome; SH3 domain; Sodium. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 494 AA 
Protein Sequence
MSHHSDDQLL QAGSDSFWEP GNYKRTTKRI EDGYKLCNDL QQLIQERADI EKGYAKSLRT 60
WSKKWGELIE KGPEYGTTEA AWKGVLTESE RISDVHMKIK DNLCNDVNSQ IKTWQKENYH 120
HTLMQIKERK DLEDLFKKAQ KPWAKLLAKV EKAKADYHSA CKTERSATNQ ERNANADSSL 180
SPDQVKKMHD RVQKTKDQVQ KCREKYEQAI AEITKYNSVY IEDMTSVFEK CQTFEKTRLQ 240
FFKEILFNVH SCLDLTKVQS LPQIYEEFSH TINNADQQKD LKWWSNNHGI NMAMNWPSFV 300
EYTEEFRDIA KGNKSKEALP AAPITLINQR PVAEDVHEYP QTNSLKKNTS TLSSVSSRAS 360
VKSEIATTQS SVTTSEAKTS AAVAGAATAT AAATAASAAS NRNSSVTNGN GKVDANPFDE 420
EEEWDESDNV LVDNGEPGVP VKALYDYEGA ESDELTFKQG DVFEKLEDED EQGWCKGRMN 480
GRVGLYPANY VETA 494 
Gene Ontology
 GO:0045211; C:postsynaptic membrane; IDA:FlyBase.
 GO:0071212; C:subsynaptic reticulum; IDA:FlyBase.
 GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.
 GO:0045887; P:positive regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.
 GO:0048488; P:synaptic vesicle endocytosis; NAS:FlyBase. 
Interpro
 IPR001060; FCH_dom.
 IPR001452; SH3_domain. 
Pfam
 PF00611; FCH
 PF00018; SH3_1 
SMART
 SM00055; FCH
 SM00326; SH3 
PROSITE
 PS50133; FCH
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.