UniProt Accession

 ATP5J_DROME; Q24407; Q9VCN0 

Genbank Protein ID

 X99665; AE014297; BT001763 

Genbank Nucleotide ID

 CAA67979.1; AAF56127.1; AAN71518.1 

Protein Name

 ATP synthase-coupling factor 6, mitochondrial 

Protein Synonyms/Alias

 ATPase subunit F6 

Gene Name

 ATPsyn-Cf6 

Gene Synonyms/Alias

 CG4412 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
54	KQKSAGGKLVDSNPD	acetylation	[1]
67	PDIERELKTELDRVA	acetylation	[1]
82	KQFGSDGKTDMLKFP	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. 

Sequence Annotation

  

Keyword

 CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 106 AA 

Protein Sequence

Gene Ontology

 GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
 GO:0046331; P:lateral inhibition; IMP:FlyBase. 

Interpro

 IPR008387; ATPase_F0-cplx_f6su_mt.
 IPR016349; ATPase_F0-cplx_f6su_mt_subgr. 

Pfam

 PF05511; ATP-synt_F6 

SMART

  

PROSITE

  

PRINTS