CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Alpha-protein kinase 3 
Protein Synonyms/Alias
  
Gene Name
 Alpk3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
204EQSWKHGKEASGEADubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1680 AA 
Protein Sequence
MGSRRAAGRG WGLGGRAGAG GDSEDDGPVW TPGPASRSYL LSVRPEASLS SNRLSHPSSG 60
RSTFCSIIAQ LTEETQPLFE TTLKSRAVSE DSDVRFTCIV TGYPEPEVTW YKDDIELDRY 120
CGLPKYEITH QGNRHTLQLY RCQEEDAAIY QASARNTKGI VSCSGVLEVG TMTEYKIHQR 180
WFAKLKRKAA AKMREIEQSW KHGKEASGEA DTLLRKISPD RFQRKRRLSG VEEAVLSTPV 240
REMEEGSSAA WQEGETESAQ HPGLGLINSF APGEAPTNGE PAPENGEDEE RGLLTYICEV 300
MELGPQNSPP KESGAKKKRK DEESKPGEQK LELEKAEGSQ CSSENVVPST DKPNSSRREK 360
STDTQPAQTQ PRGRVARGPG IESTRKTASV LGIQDKVQDV PAPAPAPVPA PALAPAPVPV 420
PAPTPVPSRS SEQVYFSLKD MFMETTRAGR SQEEEKPPPP STRVAGESPP GKTPVKSRLE 480
KVPMVSSQPT SSMVPPPIKP LNRKRFAPPK SKVESTTTSL SSQTSESMAQ SLGKALPSAS 540
TQVPTPPARR RHGTRDSPLQ GQTSHKTPGE ALESPATVAP TKSANSSSDT VSVDHDSSGN 600
QGATEPMDTE TQEDGRTLVD GRTGSRKKTH TDGKLQVDGR TQGDGAQDRA HASPRTQAGE 660
KAPTDVVTQG SERPQSDRSS WKNLVTQRRV DMQVGQMQAG ERWQQDPGDA RIQEEEKETQ 720
SAAGSIPVAF ETQSEQLSMA SLSSLPGALK GSPSGCPRES QAIECFEKST EAPCVQERSD 780
LMLRSEEAAF RSHEDGLLGP PSGNRTYPTQ LPPEGHSEHL GGQTHQRSEQ EDSLSQCPKK 840
EQPQEPLHVG LSGGHSTGLS QEVPAMPSLP GTGLTSSLQE ELPGTAASLH TNTDVPLPSR 900
DQDFPSSAPT LQLGPGSPTQ SHPPEAMATS SEGACAKEPN VDGRSSGTRS CDPGLIDSLK 960
NYLLLLLKLS SPETSEARAE SQEVADTGGL TSSSTLVPTM EVAGLSPRTS RRILERVENN 1020
HLVQSAQTLL LSPCTSRRLT GLLDREVQAG QQALAAAQCS RGPCPTPLTI PAIVVGEEGS 1080
AGEDSEERTS QESDKKGLLG EVEGHTVESR TQEPCQEEAM PGEALTGLPA ATPEELALGA 1140
RRKRFLPKVR AGSDGEANKA EERESPTVSP RGPRKGLTPG SPGTPGRERR SPTQARKASM 1200
LEVPGAEEEP ATGDLVSRSK DSGLDSEPAV DEGKQEALAK QRKAKDLLKA PQVIRKIRVE 1260
QFPDSSGSLK LWCQFFNIVS DSVLTWAKDQ HPVGEVNRSA GDEGPAALAI VQASPTDCGV 1320
YRCTIQNEHG SASTDFCLSP EVLSGFISRE EGEVGEEIEM TPMVFAKGLA DSGCWGDKLF 1380
GRLVSEELRG GGHGLQKASR AKVIYGLEPI FESGRTCIIK VSSLLVFGPS SETSLLGRNY 1440
DVTIQGCKIQ NMSREYCKIF AAEARAASGF GEVPEIIPLY LIYRPANNIP YATLEEDLGK 1500
PLQTYCSRQW GCAGAPAAAS SSEALQKCQT FQHWLYQWTN GSFLVTDLTG ADWKMTDVQI 1560
ATKLRGYQGL KESCFPALLD QFASSHQCNT YCDMLGLKPL KGPEAAHPQA KAKGSKSPSA 1620
GRKGSQLSPQ PQKKGLPSPQ GSRKSAPSSR ATLQASQAAT VQLLGQPPVQ DGSSKAQSMR 1680 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
 GO:0007507; P:heart development; IMP:MGI. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR011009; Kinase-like_dom.
 IPR004166; MHCK_EF2_kinase. 
Pfam
 PF02816; Alpha_kinase
 PF07679; I-set 
SMART
 SM00811; Alpha_kinase
 SM00408; IGc2 
PROSITE
 PS51158; ALPHA_KINASE
 PS50835; IG_LIKE 
PRINTS