| Tag | Content |
|---|
| CPLM ID | CPLM-000201 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Interleukin-13 receptor subunit alpha-1 |
Protein Synonyms/Alias | IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1 |
Gene Name | Il13ra1 |
Gene Synonyms/Alias | Il13r; Il13ra |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 383 | PDPGKIFKEMFGDQN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity (By similarity). |
Sequence Annotation | MOTIF 324 328 WSXWS motif.
MOTIF 371 379 Box 1 motif.
CARBOHYD 35 35 N-linked (GlcNAc...) (Potential).
CARBOHYD 59 59 N-linked (GlcNAc...) (Potential).
CARBOHYD 103 103 N-linked (GlcNAc...) (Potential).
CARBOHYD 136 136 N-linked (GlcNAc...) (Potential).
CARBOHYD 262 262 N-linked (GlcNAc...) (Potential).
CARBOHYD 338 338 N-linked (GlcNAc...) (Potential).
DISULFID 44 93 Potential.
DISULFID 132 142 By similarity.
DISULFID 171 183 By similarity. |
Keyword | Complete proteome; Disulfide bond; Glycoprotein; Membrane; Receptor; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 424 AA |
Protein Sequence | MARPALLGEL LVLLLWTATV GQVAAATEVQ PPVTNLSVSV ENLCTIIWTW SPPEGASPNC 60
TLRYFSHFDD QQDKKIAPET HRKEELPLDE KICLQVGSQC SANESEKPSP LVKKCISPPE 120
GDPESAVTEL KCIWHNLSYM KCSWLPGRNT SPDTHYTLYY WYSSLEKSRQ CENIYREGQH 180
IACSFKLTKV EPSFEHQNVQ IMVKDNAGKI RPSCKIVSLT SYVKPDPPHI KHLLLKNGAL 240
LVQWKNPQNF RSRCLTYEVE VNNTQTDRHN ILEVEEDKCQ NSESDRNMEG TSCFQLPGVL 300
ADAVYTVRVR VKTNKLCFDD NKLWSDWSEA QSIGKEQNST FYTTMLLTIP VFVAVAVIIL 360
LFYLKRLKII IFPPIPDPGK IFKEMFGDQN DDTLHWKKYD IYEKQSKEET DSVVLIENLK 420
KAAP 424 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0004896; F:cytokine receptor activity; IEA:InterPro. GO:0019221; P:cytokine-mediated signaling pathway; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |