CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039835
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Chondroitin sulfate synthase 2 
Protein Synonyms/Alias
  
Gene Name
 CHPF 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
176VHMYQLHKAFARAELubiquitination[1, 2]
283HPALRLQKQQLVNGYubiquitination[1, 2, 3, 4, 5]
405ADVFAPVKAHVAELEubiquitination[1, 2, 3]
441RLMDLLSKKHPLDTLubiquitination[1, 2, 4]
442LMDLLSKKHPLDTLFubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 613 AA 
Protein Sequence
MAVVTLGEER PIGHLHLALR HLLEQHGDDF DWFFLVPDTT YTEAHGLARL TGHLSLASAA 60
HLYLGRPQDF IGGEPTPGRY CHGGFGVLLS RMLLQQLRPH LEGCRNDIVS ARPDEWLGRC 120
ILDATGVGCT GDHEGVHYSH LELSPGEPVQ EGDPHFRSAL TAHPVRDPVH MYQLHKAFAR 180
AELERTYQEI QELQWEIQNT SHLAVDGDQA AAWPVGIPAP SRPASRFEVL RWDYFTEQHA 240
FSCADGSPRC PLRGADRADV ADVLGTALEE LNRRYHPALR LQKQQLVNGY RRFDPARGME 300
YTLDLQLEAL TPQGGRRPLT RRVQLLRPLS RVEILPVPYV TEASRLTVLL PLAAAERDLA 360
PGFLEAFATA ALEPGDAAAA LTLLLLYEPR QAQRVAHADV FAPVKAHVAE LERRFPGARV 420
PWLSVQTAAP SPLRLMDLLS KKHPLDTLFL LAGPDTVLTP DFLNRCRMHA ISGWQAFFPM 480
HFQAFHPAVA PPQGPGPPEL GRDTGRFDRQ AASEACFYNS DYVAARGRLA AASEQEEELL 540
ESLDVYELFL HFSSLHVLRA VEPALLQRYR AQTCSARLSE DLYHRCLQSV LEGLGSRTQL 600
AMLLFEQEQG NST 613 
Gene Ontology
 GO:0032580; C:Golgi cisterna membrane; IEA:InterPro.
 GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. 
Interpro
 IPR008428; Chond_GalNAc. 
Pfam
 PF05679; CHGN 
SMART
  
PROSITE
  
PRINTS