CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025730
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein kinase C and casein kinase substrate in neurons 3, isoform CRA_a 
Protein Synonyms/Alias
  
Gene Name
 Pacsin3 
Gene Synonyms/Alias
 mCG_13489 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
70KWRGAVEKGPQYGTLubiquitination[1]
175QTRESHAKADSSMSQubiquitination[1]
315RAISRKEKGGRSPDEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Kinase; SH3 domain; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 424 AA 
Protein Sequence
MAPEEDAGGE VLGGSFWEAG NYRRTVQRVE DGHRLCGDLV SCFQERARIE KAYAQQLADW 60
ARKWRGAVEK GPQYGTLEKA WHAFFTAAER LSELHLEVRE KLHGPDSERV RTWQRGAFHR 120
PVLGGFRESR AAEDGFRKAQ KPWLKRLKEV EASKKSYHTA RKDEKTAQTR ESHAKADSSM 180
SQEQLRKLQE RVGRCTKEAE KMKTQYEQTL AELNRYTPRY MEDMEQAFES CQAAERQRLL 240
FFKDVLLTLH QHLDLSSSDK FHELHRDLQQ SIEAASDEED LRWWRSTHGP GMAMNWPQFE 300
EWSLDTQRAI SRKEKGGRSP DEVTLTSIVP TRDGTAPPPQ SPSSPGSGQD EDWSDEESPR 360
KVATGVRVRA LYDYAGQEAD ELSFRAGEEL LKMSEEDEQG WCQGQLQSGR IGLYPANYVE 420
CVGA 424 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0008092; F:cytoskeletal protein binding; IDA:MGI.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0045806; P:negative regulation of endocytosis; IDA:MGI.
 GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IEA:Compara. 
Interpro
 IPR001060; FCH_dom.
 IPR001452; SH3_domain. 
Pfam
 PF00611; FCH
 PF00018; SH3_1 
SMART
 SM00055; FCH
 SM00326; SH3 
PROSITE
 PS50133; FCH
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.