CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007045
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 
Protein Synonyms/Alias
 PP2A, B subunit, B' delta isoform; Protein RTS1; Protein SCS1 
Gene Name
 RTS1 
Gene Synonyms/Alias
 SCS1; YOR014W; OR26.04 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
245ERLPTPTKLNPDTDLubiquitination[1]
256DTDLELIKTPQRHSSubiquitination[1]
721NLRINNDKDQYTIKNubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. 
Sequence Annotation
 MOD_RES 242 242 Phosphothreonine.
 MOD_RES 257 257 Phosphothreonine.  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 757 AA 
Protein Sequence
MMRGFKQRLI KKTTGSSSSS SSKKKDKEKE KEKSSTTSST SKKPASASSS SHGTTHSSAS 60
STGSKSTTEK GKQSGSVPSQ GKHHSSSTSK TKTATTPSSS SSSSRSSSVS RSGSSSTKKT 120
SSRKGQEQSK QSQQPSQSQK QGSSSSSAAI MNPTPVLTVT KDDKSTSGED HAHPTLLGAV 180
SAVPSSPISN ASGTAVSSDV ENGNSNNNNM NINTSNTQDA NHASSQSIDI PRSSHSFERL 240
PTPTKLNPDT DLELIKTPQR HSSSRFEPSR YTPLTKLPNF NEVSPEERIP LFIAKVDQCN 300
TMFDFNDPSF DIQGKEIKRS TLDELIEFLV TNRFTYTNEM YAHVVNMFKI NLFRPIPPPV 360
NPVGDIYDPD EDEPVNELAW PHMQAVYEFF LRFVESPDFN HQIAKQYIDQ DFILKLLELF 420
DSEDIRERDC LKTTLHRIYG KFLSLRSFIR RSMNNIFLQF IYETEKFNGV AELLEILGSI 480
INGFALPLKE EHKVFLVRIL IPLHKVRCLS LYHPQLAYCI VQFLEKDPLL TEEVVMGLLR 540
YWPKINSTKE IMFLNEIEDI FEVIEPLEFI KVEVPLFVQL AKCISSPHFQ VAEKVLSYWN 600
NEYFLNLCIE NAEVILPIIF PALYELTSQL ELDTANGEDS ISDPYMLVEQ AINSGSWNRA 660
IHAMAFKALK IFLETNPVLY ENCNALYLSS VKETQQRKVQ REENWSKLEE YVKNLRINND 720
KDQYTIKNPE LRNSFNTASE NNTLNEENEN DCDSEIQ 757 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0000780; C:condensed nuclear chromosome, centromeric region; IDA:SGD.
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0000776; C:kinetochore; IDA:SGD.
 GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
 GO:0005816; C:spindle pole body; IDA:SGD.
 GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
 GO:0032186; P:cellular bud neck septin ring organization; IMP:SGD.
 GO:0034613; P:cellular protein localization; IMP:SGD.
 GO:0051754; P:meiotic sister chromatid cohesion, centromeric; IMP:SGD.
 GO:0031578; P:mitotic spindle orientation checkpoint; IGI:SGD.
 GO:0006470; P:protein dephosphorylation; IMP:SGD.
 GO:0031107; P:septin ring disassembly; IMP:SGD.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR002554; PP2A_B56. 
Pfam
 PF01603; B56 
SMART
  
PROSITE
  
PRINTS