CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009935
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 C-type lectin domain family 4 member F 
Protein Synonyms/Alias
 C-type lectin superfamily member 13; C-type lectin 13; Kupffer cell receptor 
Gene Name
 Clec4f 
Gene Synonyms/Alias
 Clecsf13; Kclr 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
30QPQGLGPKSAALMAPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Receptor with an affinity for galactose and fucose. Could be involved in endocytosis. 
Sequence Annotation
 DOMAIN 438 538 C-type lectin.
 MOD_RES 341 341 Phosphoserine.
 CARBOHYD 86 86 N-linked (GlcNAc...) (Potential).
 CARBOHYD 92 92 N-linked (GlcNAc...) (Potential).
 CARBOHYD 115 115 N-linked (GlcNAc...) (Potential).
 CARBOHYD 132 132 N-linked (GlcNAc...) (Potential).
 CARBOHYD 209 209 N-linked (GlcNAc...) (Potential).
 CARBOHYD 255 255 N-linked (GlcNAc...) (Potential).
 DISULFID 440 536 By similarity.
 DISULFID 516 528 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Endocytosis; Glycoprotein; Lectin; Membrane; Phosphoprotein; Receptor; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MKEAELNRDM ARYCTDNQCV SLQPQGLGPK SAALMAPRTL RHVQVILALM VVTVIFSLLA 60
LFVVASQPWR PEWNKEPPSL LLRGSNNSGH DNHSQFVRET EMQVAIQRLR DYEENSSSCH 120
KEVQILKYQM DNVSSLVQLL GSHLEDVNAD ILQTKDVLKE SGALALETQA LRSSLEVASA 180
DIHSLRGDLE KANAMTSQTR GLLKSSTENT SAELHVLGRG LEEAQSEIQA LRGSLQSAND 240
LSSQTQGFLQ HSMDNISAQI QTVRDGMERA GEKMNSLKKE LETLTAQTQK ANGHLEQTDA 300
QIQGLKAELK STSSLNSRIE VVNGQMKDAS RELQTLRRDL SDVSALKSNV QMLQSNLQRA 360
KTEMQTLKAD LQATKALTAK IQGEQNRLGA LQEAVAAQKQ EQKTQNQVLQ LIAQNWKYFN 420
GNFYYFSRDK KPWREAEKFC TSQGAHLASV TSQEEQAFLV QTTSSGDHWI GLTDQGTEGI 480
WRWVDGTPFN NAQSKGFWGK NQPDNWRHRN GEREDCVHVR QQWNDMACGS SYPWVCKKST 540
GWSAARVG 548 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0006897; P:endocytosis; IEA:UniProtKB-KW. 
Interpro
 IPR001304; C-type_lectin.
 IPR016186; C-type_lectin-like.
 IPR018378; C-type_lectin_CS.
 IPR016187; C-type_lectin_fold. 
Pfam
 PF00059; Lectin_C 
SMART
 SM00034; CLECT 
PROSITE
 PS00615; C_TYPE_LECTIN_1
 PS50041; C_TYPE_LECTIN_2 
PRINTS