CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041092
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cleavage and polyadenylation-specificity factor subunit 6 
Protein Synonyms/Alias
  
Gene Name
 CPSF6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
161PVVTPCNKQFLSQFEubiquitination[1]
410CLHGIESKSYGSGSRubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 478 AA 
Protein Sequence
MADGVDHIDI YADVGEEFNQ EAEYGGHDQI DLYDDVISPS ANNGDAPEDR DYMDTLPPTV 60
GDDVGKGAAP NVVYTYTGKR IALYIGNLTW WTTDEDLTEA VHSLGVNDIL EIKFFENRAN 120
GQSKGFALVG VGSEASSKKL MDLLPKRELH GQNPVVTPCN KQFLSQFEMQ SRKTTQSGQM 180
SGEGKAGPPG AGPPNRGDRP PPPVLFPGQP FGQPPLGPLP PGPPPPVPGY GPPPGPPPPQ 240
QGPPPPPGPF PPRPPGPLGP PLTLAPPPHL PGPPPGAPPP APHVNPAFFP PPTNSGMPTS 300
DSRGPPPTDP YGRPPPYDRG DYGPPGREMD TARTPLSEAE FEEIMNRNRA ISSSAISRAV 360
SDASAGDYGS AIETLVTAIS LIKQSKVSAD DRCKVLISSL QDCLHGIESK SYGSGSRRER 420
SRERDHSRSR EKSRRHKSRS RDRHDDYYRE RSRERERHRD RDRDRDRERD REREYRHR 478 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS