CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039212
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Itgav 
Protein Synonyms/Alias
  
Gene Name
 Itgav 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
741SEMDTSVKFDLKIQSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell adhesion; Complete proteome; Integrin; Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1042 AA 
Protein Sequence
MADPGRLLLR PRPGGLLLLL LGLLLPFAGS FNLDVESPAE YAGPEGSYFG FAVDFFVPST 60
SSRMFLLVGA PKANTTQPGI IEGGQVLKCD CSSSRRCQPI EFDSTGNRDY AKDDPLEFKS 120
HQWFGASVRS KQDKILACAP LYHWRTEMKQ EREPVGTCFL QDGTKTVEYA PCRSKNIDAD 180
GQGFCQGGFS IDFTKADRVL LGGPGSFYWQ GQLISDQVAE IISKYDPNVY SIKYNNQLAT 240
RTAQAIFDDS YLGYSVAVGD FNGDGIEDFV SGVPRAARTL GMVYIYDGKN MSSLHNFTGE 300
QMAAYFGFSV AATDINGDDY ADVFIGAPLF MDRGSDGKLQ EVGQVSVSLQ RASGDFQTTK 360
LNGFEVFARF GSAIAPLGDL DQDGFNDIAI AAPYGGEDKK GLVYIFNGRS TGLNSVPSQI 420
LQGQWAAQSM PPSFGYSMKG ATDVDRNGYP DLVVGAFGVD RAVLYRARPV VTVNAGLEVY 480
PSILNQDNKI CPLPGTALKV SCHCTRNTKL AGRAEIRNPG HFQVELLLDK LKQKGAIRRA 540
LFLHNRSPGH SKDMTVFRGG QTQCEELVAY LRPISKGRVY SCQMDVRRGY IVKKPISGNI 600
TGLSNLQNSP VSKNLRREAH ILLDCGEDNV CKPKLEVSVD SDQKKIYIGD DNPLTLTVKA 660
QNQGEGAYEA ELIVSIPPQA DFIGVVRNNE ALARLSCAFK TENQTRQVVC DLGNPMKAGT 720
QLLAGLRFSV HQQSEMDTSV KFDLKIQSSN SFDNVSPVVS YKVDLAVLAA VEIRGVSSPD 780
HIFLPIPNWE YKETPETEED VGPVVQHIYE LRNNGPSSFS KAILNLQWPY KYNNNTLLYI 840
LHYDIDGPMN CTADTEINPL RIKTPEKNDT AAEQGGRNHL ITKRDLSLSE GDVHTLGCGT 900
AQCLQITCQV GRLDRGKSAI LYVKSLLWTE TFMNKENQNH SYSLKSSASF NIIEFPYKNL 960
PIEDLFNSTL VTTNITWGIQ PAPMPVPVWV IILAVLAGLL LLAVLVFVMY RMGFFKRVRP 1020
PQEEQEREQL QPHENGEGNS ET 1042 
Gene Ontology
 GO:0008305; C:integrin complex; IEA:InterPro.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW. 
Interpro
 IPR013517; FG-GAP.
 IPR013519; Int_alpha_beta-p.
 IPR000413; Integrin_alpha.
 IPR013649; Integrin_alpha-2.
 IPR018184; Integrin_alpha_C_CS. 
Pfam
 PF01839; FG-GAP
 PF00357; Integrin_alpha
 PF08441; Integrin_alpha2 
SMART
 SM00191; Int_alpha 
PROSITE
 PS51470; FG_GAP
 PS00242; INTEGRIN_ALPHA 
PRINTS
 PR01185; INTEGRINA.