CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044361
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable fibrosin-1 
Protein Synonyms/Alias
  
Gene Name
 FBRS 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
528MFEKYPGKMEGLFRHubiquitination[1, 2, 3]
588VPSGLSQKGTQIPDHubiquitination[1, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 980 AA 
Protein Sequence
METAAAAAPG PGWAAEGERR RRRCSRRDRD REQRRRRGPG GDAPRALLAA PRGSSSSSSP 60
PPPARPWSSA SSGERPGGPR RRRPRPRPRP PRPRARKRPA GSGSRGEEEE EEEEEGGADD 120
GEAEEEPEEE EEEEEDLIDG FAIASFATLE ALQKDASLQP PERLEHRLKH SGKRKRGGSS 180
GATGEPGDSS DREPGRPPGD RARKWPNKRR RKEASSRHSL EAGYICDAES DLDERVSDDD 240
LDPSFTVSTS KASGPHGAFN GNCEAKLSVV PKVSGLERSQ EQPPGPDPLL VPFPPKEPPP 300
PPVPRPPVSP PAPLPATPSL PPPPQPQLQL RVSPFGLRTS PYGSSLDLST GSSSRPPPKA 360
PAPPVAQPPP SSSSSSSSSS SASSSSAQLT HRPPTPSLPL PLSTHSFPPP GLRPPPPPHH 420
PSLFSPGPTL PPPPPLLQVP GHPGASAANA LSEQDLIGQD LNSRYLNAQG GPEVVGAGGS 480
ARPLAFQFHQ HNHQHQHTHQ HTHQHFTPYP PGLLPPHGPH MFEKYPGKME GLFRHNPYTA 540
FPPAVPGLPP GLPPAVSFGS LQGAFQPKST NPELPPRLGP VPSGLSQKGT QIPDHFRPPL 600
RKPGKWCAMH VRVAYMILRH QEKMKGDSHK LDFRNDLLPC LPGPYGALPP GQELSHPASL 660
FTATGAVHAA ANPFTAAPGA HGPFLSPSTH IDPFGRPTSF ASLAALSNGA FGGLGSPTFN 720
SGAVFAQKES PGAPPAFASP PDPWGRLHRS PLTFPAWVRP PEAARTPGSD KERPVERREP 780
SITKEEKDRD LPFSRPQLRV SPATPKARAG EEGPRPTKES VRVKEERKEE AAAAAAAAAA 840
AAAAAAAAAT GPQGLHLLFE RPRPPPFLGP SPPDRCAGFL EPTWLAAPPR LARPPRFYEA 900
GEELTGPGAV AAARLYGLEP AHPLLYSRLA PPPPPAAAPG TPHLLSKTPP GALLGAPPPL 960
VPAPRPSSPP RGPGPARADR 980 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Compara. 
Interpro
 IPR023246; AUTS2. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR02044; FIBROSIN1LPF.