CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007671
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Melanoma-associated antigen 9 
Protein Synonyms/Alias
 Cancer/testis antigen 1.9; CT1.9; MAGE-9 antigen 
Gene Name
 MAGEA9; MAGEA9B 
Gene Synonyms/Alias
 MAGE9; MAGEA9A 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131RVKEPVTKAEMLESVubiquitination[1]
243MFYGEPRKLLTQDWVubiquitination[1, 2]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. 
Sequence Annotation
 DOMAIN 108 307 MAGE.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Tumor antigen. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 315 AA 
Protein Sequence
MSLEQRSPHC KPDEDLEAQG EDLGLMGAQE PTGEEEETTS SSDSKEEEVS AAGSSSPPQS 60
PQGGASSSIS VYYTLWSQFD EGSSSQEEEE PSSSVDPAQL EFMFQEALKL KVAELVHFLL 120
HKYRVKEPVT KAEMLESVIK NYKRYFPVIF GKASEFMQVI FGTDVKEVDP AGHSYILVTA 180
LGLSCDSMLG DGHSMPKAAL LIIVLGVILT KDNCAPEEVI WEALSVMGVY VGKEHMFYGE 240
PRKLLTQDWV QENYLEYRQV PGSDPAHYEF LWGSKAHAET SYEKVINYLV MLNAREPICY 300
PSLYEEVLGE EQEGV 315 
Gene Ontology
  
Interpro
 IPR002190; MAGE.
 IPR021072; Melanoma_ass_antigen_N. 
Pfam
 PF01454; MAGE
 PF12440; MAGE_N 
SMART
  
PROSITE
 PS50838; MAGE 
PRINTS