CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024602
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycolipid transfer protein 
Protein Synonyms/Alias
 GLTP 
Gene Name
 GLTP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
10LLAEHLLKPLPADRQacetylation[1]
66VYDTDPAKFKTLQNIacetylation[1]
158ALYAAPYKSDFLKALubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides (By similarity). 
Sequence Annotation
 REPEAT 45 55 1.
 REPEAT 56 66 2.
 REGION 45 66 2 X 12 AA approximate tandem repeats.
 REGION 48 55 Glycolipid binding (By similarity).
 BINDING 140 140 Glycolipid (By similarity).
 BINDING 207 207 Glycolipid (By similarity).
 MOD_RES 2 2 N-acetylalanine (By similarity).  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Lipid transport; Reference proteome; Repeat; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 209 AA 
Protein Sequence
MALLAEHLLK PLPADRQIET GPFLEAVAHL PPFFDCLGSP VFTPIKADIS GNITKIKAVY 60
DTDPAKFKTL QNILEVEKGM YGAEWPKVGA TLALLWLKRG LRFIQVFLQS ICDGERDENH 120
PNLIRVNANK AYEMALKKYH GWLVQKIFKA ALYAAPYKSD FLKALSKGQN VTEEECLEKI 180
RLFLVNYTAT IDAIYEMYTK MNAELDYTV 209 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0051861; F:glycolipid binding; IEA:Compara.
 GO:0017089; F:glycolipid transporter activity; IEA:Compara.
 GO:0046836; P:glycolipid transport; IEA:Compara. 
Interpro
 IPR014830; Glycolipid_transfer_prot_dom. 
Pfam
 PF08718; GLTP 
SMART
  
PROSITE
  
PRINTS