Tag | Content |
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CPLM ID | CPLM-007151 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | AP-1 accessory protein LAA1 |
Protein Synonyms/Alias | Large AP-1 accessory protein 1 |
Gene Name | LAA1 |
Gene Synonyms/Alias | YJL207C; HRD550; J0312 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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1546 | NDSTVQVKNDSKENS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the trans-Golgi network (TGN)-endosome transport. Important for the correct localization of the adapter protein complex AP-1. |
Sequence Annotation | |
Keyword | Complete proteome; Golgi apparatus; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2014 AA |
Protein Sequence | MANRSLKKVI ETSSNNGHDL LTWITTNLEK LICLKEVNDN EIQEVKEIHT QLDEFVRYIS 60 VLENTDDLEL HSVFISLSQL YTISIWRLKD EYPGVVFDSA AFLTNVLCEE DVSIDDGDTD 120 PNQKKKKKKS STKKKKYIYS PAKDIACTIL VQLFENFGSS ISSLIPLLFN AIFKNLKKIM 180 EKSKYYHATF MTTLLQLFNA ILRNSNNDDK ILDPATYAKF SKLSKTVFDS ISTDEKDFSV 240 TFVSVLIECW TAHFKQTNFI REHSHDIIET IYSRFTEGEI GVYGFANDET RIFTAKSLAE 300 ILFDYYFSKN ILTLQEVWSI YVKIFLNCDT RDVESGCFES IIHLINLNLL ADNTFLSNSK 360 YLDIVLSLSG VFSSYEVNNR SMNTLSRYLR YFQHMHEVIL PHLNDSAKTQ MLYYILGCSD 420 TYQSSSKSDS ASNFKYSIDA KPETQWLTLL QLDFTYVLIS DLGSTFTTEE NTVKEIRDKL 480 VDLATCEIFT IRVHTVEILK VFLNNCPEYL SETIENSLRA LSTDFKSTGK FIFHKNHGHA 540 FIIANLIKGA ESDYISYELI MRITVFSTSF IKNNTTSTSS NLYFKGLLCW ILLIGLMNYK 600 DEQYLKLQIP QLFLFWKVLL THTYTYHDED ELYKNLEIRN HALTCLLTYL SNTTIDKEMA 660 KQVSYLLTKC SNFNHSIDLK SKNIDNALLH NENRILQVYL KLEKYINSDF NSSLLILIVK 720 NFSDPNLYTE SSSSVLGSLK DIGNRKVSNK DDMESNIVLE SSINTLLRQN NGFAFGLSSK 780 ITGDRIVNLS MSSAYKYDES ISGSWPSKDY NWYNIFEVEV SKPISPILSL DSLILLYGSG 840 SYSQIDRYAP QVTTSLIDSS MELFSSVFPF LNSKIQYSIM ETLNLSMFSK MTTPLRSVAV 900 AANVCSALHN ALRIMQENNL ELDYSVGQLI IESIKKIQFF NDIFLTKIKA DCVGLLTAAI 960 ARTLGDEERQ KFLTEQSRIF IKNVADMDEP YLRMFHVLSL ATIFKYNSQY ANFEEYFDVI 1020 FALMRDPHPV VHSWSLKAMH ILLEKHLVID LKTAALLLSS MEELLVQDKY GIYGRSTLRC 1080 NYNRDFNSHV AIGEISRTLT ETVGPNFLEL NTKVLDSFRN ITLSMLISNN ILNSITSIKM 1140 FENIATFKMK NILNYEIFIL ASKSIIKSSI VTGIGSSYFD TTFTGSNELI SRTSSLKGAF 1200 ENFDLLTLLY KLQMEEFFMK EMENLSWRYL ALFPNSGSVK NYFTEWILHT FKRDNHWFDK 1260 LYSIFNMSLG RLFQSYNRDV SALLEVNGLK KSSEKEIKGE EEESIANVNQ LTDTDAGGLD 1320 SENLQWKSRQ IILNLILMLC LESEKYENLL LALSNKIADL IKISFRGSTV RNEGMKLTGL 1380 HILNFVLKNY STMRDPQVPG SSILEQQEAQ ITSALMPAFS KGSSPTVMSF AITVAAEVLA 1440 SNIMPPDKLG RISQLLIDLL GNFKDPNSGI RIGEAIIVTP KAKRKIELAV LDAWAEVVQR 1500 SITSSNDALF SFTRKYWSIL VPLWIISLRE YMMIKYNDND STVQVKNDSK ENSLIEPRST 1560 KIELYEPVWL NFVEALGCTL DSDVQVILAS LNDEELEYFL FILFSQCLEA IVKNIDDHSV 1620 KMQVLPALHN VLKSNLCIKS IFEDDIITEV VEIMDRLIST GDSKEEFLLV DIISDLIIGY 1680 SKCNATPETF LQDIDKLYEL LRLLMTIISE RLPFIKYNVL TSEEDDNEIK ISPTDISLLK 1740 KTFIAFESNI SNFDNMFKVD LYSCLLFIIG KIYECSHREV IIPIILPLFK ALVKALTESE 1800 DEKNIVLLEI FYGSIKDVIY HKLDSKNKVA TILILLSNGY SKLSFQELNQ CANILSEALN 1860 NPATQPIALQ GFKRIISNIF KYPLLQYFMK LVIKRFFQDI QTNDSLSQAS IKTKLIIQFS 1920 EEVIKQDHQK ASLSIALCLS FFAAYHSAYT EKIDNEVASG IVALAKLDKN SFKEAISSTI 1980 SPQQKAIIGS VMEAYVKSQS LGSVEEAFQL KSFD 2014 |
Gene Ontology | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0008104; P:protein localization; IMP:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0042147; P:retrograde transport, endosome to Golgi; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |