UniProt Accession

 CTR1_YEAST; P49573; D6W4C2 

Genbank Protein ID

 U02511; U40828; AY693062; BK006949 

Genbank Nucleotide ID

 AAA17369.1; AAB68064.1; AAT93081.1; DAA11538.1 

Protein Name

 Copper transport protein CTR1 

Protein Synonyms/Alias

 Copper transporter 1 

Gene Name

 CTR1 

Gene Synonyms/Alias

 YPR124W; P9642.3 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
302	QREIQKAKSCPGFGN	ubiquitination	[1]
345	LEKNNESKVAISENN	ubiquitination	[1, 2]
354	AISENNQKKTPTQEE	ubiquitination	[1]
355	ISENNQKKTPTQEEG	ubiquitination	[1]
371	NCATDSGKNQANIER	ubiquitination	[1, 2]
385	RDILENSKLQEQSGN	ubiquitination	[1]
402	QNLLPAEKFTHN***	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

 Required for high affinity copper (probably reduced Cu I) transport into the cell. 

Sequence Annotation

 REPEAT 9 27 1.
 REPEAT 28 46 2.
 REPEAT 47 65 3.
 REGION 9 65 3 X 19 AA tandem repeats of S-M-X-M-X-A-
 MOD_RES 344 344 Phosphoserine.
 MOD_RES 349 349 Phosphoserine.
 MOD_RES 356 356 Phosphothreonine.
 MOD_RES 369 369 Phosphoserine.
 CARBOHYD 113 113 N-linked (GlcNAc...) (Potential).
 CARBOHYD 148 148 N-linked (GlcNAc...) (Potential).  

Keyword

 Complete proteome; Copper; Copper transport; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 406 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0015088; F:copper uptake transmembrane transporter activity; IMP:SGD.
 GO:0015677; P:copper ion import; IMP:SGD. 

Interpro

 IPR007274; Cop_transporter. 

Pfam

 PF04145; Ctr 

SMART

  

PROSITE

  

PRINTS