CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025241
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Prkar1a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
199RQIQCLQKTGIRTDSubiquitination[1]
221PPPNPVVKGRRRRGAubiquitination[1]
351VKAKTNVKLWGIDRDubiquitination[1]
373GSTLRKRKMYEEFLSubiquitination[1]
381MYEEFLSKVSILESLubiquitination[1]
390SILESLDKWERLTVAubiquitination[1]
478RGPLKCVKLDRPRFEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 510 AA 
Protein Sequence
MTGPSPEPRV LRGSTQDARS VHQEHLSIRL RSAVVDPLGP PPLPTAGISL SAQRPVTPSP 60
SLPSHSTQGG VAHLSPNRPT WVCGRRVEGR EKRQRRGGRQ TQEPPRNRGE AEISEQLNNL 120
EDPPPHLRTM ASGSMATSEE ERSLRECELY VQKHNIQALL KDSIVQLCTT RPERPMAFLR 180
EYFERLEKEE ARQIQCLQKT GIRTDSREDE ISPPPPNPVV KGRRRRGAIS AEVYTEEDAA 240
SYVRKVIPKD YKTMAALAKA IEKNVLFSHL DDNERSDIFD AMFPVSFIAG ETVIQQGDEG 300
DNFYVIDQGE MDVYVNNEWA TSVGEGGSFG ELALIYGTPR AATVKAKTNV KLWGIDRDSY 360
RRILMGSTLR KRKMYEEFLS KVSILESLDK WERLTVADAL EPVQFEDGQK IVVQGEPGDE 420
FFIILEGTAA VLQRRSENEE FVEVGRLGPS DYFGEIALLM NRPRAATVVA RGPLKCVKLD 480
RPRFERVLGP CSDILKRNIQ QYNSFVSLSV 510 
Gene Ontology
 GO:0005952; C:cAMP-dependent protein kinase complex; IEA:Compara.
 GO:0005737; C:cytoplasm; TAS:MGI.
 GO:0031594; C:neuromuscular junction; IDA:MGI.
 GO:0030552; F:cAMP binding; IEA:Compara.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; IDA:MGI.
 GO:0060038; P:cardiac muscle cell proliferation; IMP:MGI.
 GO:0007143; P:female meiosis; IEA:Compara.
 GO:0001707; P:mesoderm formation; IMP:MGI.
 GO:0045835; P:negative regulation of meiosis; IEA:Compara.
 GO:0006469; P:negative regulation of protein kinase activity; IMP:MGI.
 GO:0009887; P:organ morphogenesis; TAS:MGI.
 GO:0006468; P:protein phosphorylation; TAS:MGI.
 GO:0045214; P:sarcomere organization; IMP:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR002373; cAMP/cGMP_kin.
 IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
 IPR018490; cNMP-bd-like.
 IPR018488; cNMP-bd_CS.
 IPR000595; cNMP-bd_dom.
 IPR014710; RmlC-like_jellyroll. 
Pfam
 PF00027; cNMP_binding
 PF02197; RIIa 
SMART
 SM00100; cNMP
 SM00394; RIIa 
PROSITE
 PS00888; CNMP_BINDING_1
 PS00889; CNMP_BINDING_2
 PS50042; CNMP_BINDING_3 
PRINTS
 PR00103; CAMPKINASE.