| Tag | Content |
|---|
| CPLM ID | CPLM-012901 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial |
Protein Synonyms/Alias | PDHE1-B; Protein MACCI-BOU |
Gene Name | PDH2 |
Gene Synonyms/Alias | MAB1; At5g50850; K16E14.1 |
Created Date | July 27, 2013 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
NCBI Taxa ID | 3702 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 34 | RSYAAGAKEMTVRDA | ubiquitination | [1] | | 247 | VTIVTFSKMVGFALK | ubiquitination | [1] | | 254 | KMVGFALKAAEKLAE | ubiquitination | [1] |
|
Reference | [1] Multidimensional protein identification technology (MudPIT) analysis of ubiquitinated proteins in plants. Maor R, Jones A, Nühse TS, Studholme DJ, Peck SC, Shirasu K. Mol Cell Proteomics. 2007 Apr;6(4):601-10. [ PMID: 17272265] |
Functional Description | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). |
Sequence Annotation | BINDING 92 92 Thiamine pyrophosphate (By similarity).
CROSSLNK 34 34 Glycyl lysine isopeptide (Lys-Gly)
CROSSLNK 247 247 Glycyl lysine isopeptide (Lys-Gly)
CROSSLNK 254 254 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Complete proteome; Glycolysis; Isopeptide bond; Mitochondrion; Oxidoreductase; Pyruvate; Reference proteome; Thiamine pyrophosphate; Transit peptide; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 363 AA |
Protein Sequence | MLGILRQRAI DGASTLRRTR FALVSARSYA AGAKEMTVRD ALNSAIDEEM SADPKVFVMG 60
EEVGQYQGAY KITKGLLEKY GPERVYDTPI TEAGFTGIGV GAAYAGLKPV VEFMTFNFSM 120
QAIDHIINSA AKSNYMSAGQ INVPIVFRGP NGAAAGVGAQ HSQCYAAWYA SVPGLKVLAP 180
YSAEDARGLL KAAIRDPDPV VFLENELLYG ESFPISEEAL DSSFCLPIGK AKIEREGKDV 240
TIVTFSKMVG FALKAAEKLA EEGISAEVIN LRSIRPLDRA TINASVRKTS RLVTVEEGFP 300
QHGVCAEICA SVVEESFSYL DAPVERIAGA DVPMPYAANL ERLALPQIED IVRASKRACY 360
RSK 363 |
Gene Ontology | GO:0048046; C:apoplast; IDA:TAIR. GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:TAIR. GO:0005730; C:nucleolus; IDA:TAIR. GO:0005774; C:vacuolar membrane; IDA:TAIR. GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:EC. GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IEA:InterPro. GO:0042742; P:defense response to bacterium; IEP:TAIR. GO:0006096; P:glycolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |