UniProt Accession

 Q6AXR9_RAT; Q6AXR9 

Genbank Protein ID

 AABR06107863; BC079353 

Genbank Nucleotide ID

 AAH79353.1 

Protein Name

 Protein Ube2a 

Protein Synonyms/Alias

 Ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae) 

Gene Name

 Ube2a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
76	FTEEYPNKPPTVRFV	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Ligase; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 162 AA 

Protein Sequence

Gene Ontology

 GO:0033503; C:HULC complex; IEA:Compara.
 GO:0000790; C:nuclear chromatin; IEA:Compara.
 GO:0001741; C:XY body; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0006281; P:DNA repair; IEA:Compara.
 GO:0033522; P:histone H2A ubiquitination; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0060135; P:maternal process involved in female pregnancy; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0051865; P:protein autoubiquitination; IEA:Compara.
 GO:0070979; P:protein K11-linked ubiquitination; IEA:Compara.
 GO:0070936; P:protein K48-linked ubiquitination; IEA:Compara.
 GO:0009411; P:response to UV; IEA:Compara. 

Interpro

 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 

Pfam

 PF00179; UQ_con 

SMART

  

PROSITE

 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 

PRINTS