CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025568
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 445 
Protein Synonyms/Alias
  
Gene Name
 Zfp445 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
385NNDILELKHVKCVSVubiquitination[1]
885EYGLHSDKPGLSYCQubiquitination[1]
904NIQELSGKLRKECDNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Nucleus; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 986 AA 
Protein Sequence
MPPGRWHAAR SAQVSREQGC LRMVKEEEED GYISMQTARP QTLNRPGQEL FRQLFRQLRY 60
HESSGPLETL SRLQELCRWW MRPDVLSKAQ MLELLVLEQF LSILPGELRT WVQLHCPESG 120
AEVVALLEEL QRDLDGTPLK DPCLTQNPDV HWIGTSALQP AQIWSPASHL KNSSALEDHL 180
ETSHGIGICD VLAEQTDSPA VSVPDYFQLE EGIEYQEALT FQDVEVTFSQ EEWGCLNSAQ 240
RNLYRDVILE NYGNVVSVVG SSPKPALISW LEARKPWGVN ICTVQLKRDA DAAPEGGKLQ 300
IKPNKFILKQ KPSEYIEACV KTSVSPETSV SEETGLKESF KQKSRLQTSC GDSIQMKEMK 360
EGADISQRTG RESEVLRNND ILELKHVKCV SVSRKRLSFK HGYDRNFRKS SHHYNNKYGE 420
GLRGTGEGFG VYQNTGLKEN GKDRYGETSR KSWHAHPEHR QPSYSEEGLF QCRVCGKAFK 480
WRSNRIRHEK IHTGVKPYQC SLCEKAFQRL SSYRLHQKTH SKQKRGSSKY KNALTCSLDV 540
SHHLTDRDER KHLHCNQCGK NFSCKSYAIE HQRIHTQEKP YKCTRCRKTI RWKSNFSRHM 600
KLHHKEVYKQ EKRQEDFKQS YRQSQVISTV EKTFPCQNCG KTFTQKKSLI EHQRIHTGEK 660
PYQCSGCGET FTYRSSYIIH MKRTQHAIKI KPEHGCLTFS QGAVFPIPRG SHNTEGSNKC 720
KYCGKAFHNR SFLLIHERVH TREKPYQCRE CEKAFRWSSN LYRHQRKHFL HKRYKYRESK 780
ETSNLQSKIL IDQKPFWCQE CGKTFTRKRS LLDHKGIHSG ERRFKCNLCE KSFDRNYRLV 840
NHQRIHTTEQ PQWRDKDFVG IHARSVDQRK HSNTLQSEYG LHSDKPGLSY CQDVRLNIQE 900
LSGKLRKECD NPSDESSKSI AFQNVPTKKK ACHKCSTCGK TFKKHSHLIS HKRCHTKERP 960
FKCIVCGKTF RWSSNLTRHM KNHVRN 986 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0016032; P:viral reproduction; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR008916; Retrov_capsid_C.
 IPR003309; Tscrpt_reg_SCAN.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF02023; SCAN
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00431; SCAN
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS50804; SCAN_BOX
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS