CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000233
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 C2 domain-containing protein 2-like 
Protein Synonyms/Alias
 Transmembrane protein 24 
Gene Name
 C2CD2L 
Gene Synonyms/Alias
 KIAA0285; TMEM24; DLNB23 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
271GGLVPSEKPPMMPQAubiquitination[1]
352QSRELTLKVLRSSSCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 MOD_RES 358 358 Phosphoserine (By similarity).
 MOD_RES 417 417 Phosphothreonine.
 MOD_RES 464 464 Phosphoserine.
 MOD_RES 613 613 Phosphoserine (By similarity).
 MOD_RES 619 619 Phosphoserine (By similarity).
 MOD_RES 623 623 Phosphoserine.
 MOD_RES 660 660 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 706 AA 
Protein Sequence
MDPGWGQRDV GWAALLILFA ASLLTVFAWL LQYARGLWLA RARGDRGPGP ALAGEPAGSL 60
RELGVWRSLL RLRATRAGAA EEPGVRGLLA SLFAFKSFRE NWQRAWVRAL NEQACRNGSS 120
IQIAFEEVPQ LPPRASISHV TCVDQSEHTM VLRCQLSAEE VRFPVSVTQQ SPAAVSMETY 180
HVTLTLPPTQ LEVNLEEIPG EGLLISWAFT DRPDLSLTVL PKLQARERGE EQVELSTIEE 240
LIKDAIVSTQ PAMMVNLRAC SAPGGLVPSE KPPMMPQAQP AIPRPNRLFL RQLRASHLGN 300
ELEGTEELCC VAELDNPMQQ KWTKPARAGS EVEWTEDLAL DLGPQSRELT LKVLRSSSCG 360
DTELLGQATL PVGSPSRPLS RRQLCPLTPG PGKALGPAAT MAVELHYEEG SPRNLGTPTS 420
STPRPSITPT KKIELDRTIM PDGTIVTTVT TVQSRPRIDG KLDSPSRSPS KVEVTEKTTT 480
VLSESSGPSN TSHSSSPGDS HLSNGLDPVA ETAIRQLTEP SGRVAKKTPT KRSTLIISGV 540
SKVPIAQDEL ALSLGYAASL EASVQDDAGT SGGPSSPPSD PPAMSPGPLD ALSSPTSVQE 600
ADETTRSDIS ERPSVDDIES ETGSTGALET RSLKDHKVSF LRSGTKLIFR RRPRQKEAGL 660
SQSHDDLSNA TATPSVRKKA GSFSRRLIKR FSFKSKPKAN GNPSPQL 707 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR008973; C2_Ca/lipid-bd_dom_CaLB. 
Pfam
  
SMART
  
PROSITE
  
PRINTS