CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037096
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutathione peroxidase 
Protein Synonyms/Alias
  
Gene Name
 GPX8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
77EVESFARKNYGVTFPubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Peroxidase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 158 AA 
Protein Sequence
MEPLAAYPLK CSGPRAKVSL VVNVASDCQL TDRNYLGLKE LHKEFGPSHF SVLAFPCNQF 60
GESEPRPSKE VESFARKNYG VTFPIFHKIK ILGSEGEPAF RFLVDSSKKE PRWNFWKYLV 120
NPEGQVVKFW KPEEPIEVIR PDIAALVRQV IIKKKEDL 158 
Gene Ontology
 GO:0004602; F:glutathione peroxidase activity; IEA:InterPro.
 GO:0006979; P:response to oxidative stress; IEA:InterPro. 
Interpro
 IPR013376; Glut_perox_Gpx7.
 IPR000889; Glutathione_peroxidase.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF00255; GSHPx 
SMART
  
PROSITE
 PS00763; GLUTATHIONE_PEROXID_2
 PS51355; GLUTATHIONE_PEROXID_3 
PRINTS
 PR01011; GLUTPROXDASE.