CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009818
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized HTH-type transcriptional regulator YhaJ 
Protein Synonyms/Alias
  
Gene Name
 yhaJ 
Gene Synonyms/Alias
 b3105; JW3076 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
62DRSGHRTKFTNVGRMacetylation[1]
219LTVQLLDKQPRLTVSacetylation[1]
231TVSTIEDKRQALLAGacetylation[1]
251MPYPMVEKDIAEGRLacetylation[1]
293WCLREIPKLFNGK**acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 7 64 HTH lysR-type.
 DNA_BIND 24 43 H-T-H motif (By similarity).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
MAKERALTLE ALRVMDAIDR RGSFAAAADE LGRVPSALSY TMQKLEEELD VVLFDRSGHR 60
TKFTNVGRML LERGRVLLEA ADKLTTDAEA LARGWETHLT IVTEALVPTP AFFPLIDKLA 120
AKANTQLAII TEVLAGAWER LEQGRADIVI APDMHFRSSS EINSRKLYTL MNVYVAAPDH 180
PIHQEPEPLS EVTRVKYRGI AVADTARERP VLTVQLLDKQ PRLTVSTIED KRQALLAGLG 240
VATMPYPMVE KDIAEGRLRV VSPESTSEID IIMAWRRDSM GEAKSWCLRE IPKLFNGK 298 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR005119; LysR_subst-bd.
 IPR000847; Tscrpt_reg_HTH_LysR.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00126; HTH_1
 PF03466; LysR_substrate 
SMART
  
PROSITE
 PS50931; HTH_LYSR 
PRINTS