UniProt Accession

 MSRA_YEAST; P40029; D3DLU2 

Genbank Protein ID

 U18796; AY692798; BK006939 

Genbank Nucleotide ID

 AAB64577.1; AAT92817.1; DAA07696.1 

Protein Name

 Peptide methionine sulfoxide reductase 

Protein Synonyms/Alias

 Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase; Protein-methionine-S-oxide reductase 

Gene Name

 MXR1 

Gene Synonyms/Alias

 YER042W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
129	AHSDADLKELAKIKE	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Also able to reduce dimethyl sulfoxide (DMSO) as well, with DMS as the product. 

Sequence Annotation

 MOD_RES 58 58 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Oxidoreductase; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 184 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0008113; F:peptide-methionine (S)-S-oxide reductase activity; IDA:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD. 

Interpro

 IPR002569; Met_Sox_Rdtase_MsrA. 

Pfam

 PF01625; PMSR 

SMART

  

PROSITE

  

PRINTS