CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042476
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 MMS19 nucleotide excision repair protein homolog 
Protein Synonyms/Alias
  
Gene Name
 MMS19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71LYRLSFLKEDSQSCRacetylation[1, 2]
71LYRLSFLKEDSQSCRubiquitination[2, 3, 4]
463HAAPQDVKPNYLKGLubiquitination[3, 4, 5]
561TPVLLPYKPQVIRALubiquitination[2, 4]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 598 AA 
Protein Sequence
XWSYEDKDQR PLNGFKDQLC SLVFMALTDP STQLQLVGIR TLTVLGAQPD LLSYEDLELA 60
VGHLYRLSFL KEDSQSCRVA ALEASGTLAA LYPVAFSSHL VPKLAEELRV GESNLTNGDE 120
PTQCSRHLCC LQALSAVSTH PSIVKETLPL LLQHLWQVNR GNMVAQSSDV IAVCQSLRQM 180
AEKCQQDPES CWYFHQTAIP CLLALAVQAS MPEKEPSVLR KVLLEDEVLA AMVSVIGTAT 240
THLSPELAAQ SVTHIVPLFL DGNVSFLPEN SFPSRFQPFQ DGSSGQRRLI ALLMAFVCSL 300
PRNVEIPQLN QLMRELLELS CCHSCPFSST AAAKCFAGLL NKHPAGQQLD EFLQLAVDKV 360
EAGLGSGPCR SQAFTLLLWV TKALVLRYHP LSSCLTARLM GLLSDPELGP AAADGFSLLM 420
SDCTDVLTRA GHAEVRIMFR QRFFTDNVPA LVQGFHAAPQ DVKPNYLKGL SHVLNRLPKP 480
VLLPELPTAL SCPDCVVQLS TLSCLQPLLL EAPQVMSLHV DTLVTKFLNL SSSPSMAVRI 540
AALQCMHALT RLPTPVLLPY KPQVIRALAK PLDDKKRLVR KEAVSARGEW FLLGSPGS 598 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
  
SMART
  
PROSITE
  
PRINTS