CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038698
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cardiomyopathy-associated protein 5 
Protein Synonyms/Alias
  
Gene Name
 Cmya5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
255LPKGYVIKEIHYRRGubiquitination[1]
2899AEREIRRKPETSFWEubiquitination[1]
3166FLENLQEKSLRIEAFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3676 AA 
Protein Sequence
MESGDSGLAA QGFLGWGADE EVAQELETEE ESEGEGEETA AESEEEPDAR LSDEDEEGKT 60
KQECIVSDPS FSMVAVQRED SGITWETNSS RSSTPWASGE SQTSGICSLE GSALTSPPGS 120
VSFIMDEVKR TRKRTQKSKR GSPSLRRKGS KKRNSLESQD VLTNQEDGPS ISESPVLNIE 180
NEKSSIGTYD KTRRKKTASN TPPITGAIYK EHKPLVLKPV YIGTVQYKIK MFNSVKEELI 240
PLQFYGTLPK GYVIKEIHYR RGKDSSISLE PDLSNGGSNI VPQRKLAQSP EEDKVRELAP 300
PWRGALSKGS RTSLFSHEEQ KKTYADSNLN VPSSTEHAFP SSARNDTADQ EENLSLPQMM 360
PQQPADESKT HRMEPPSIPA TMVLERAKEE LEQNAQGKES SEDDASVLTG SADDVQQEGL 420
VSVNHSMPWE AEKESLETGP PRPAPAIQEK FEPDMEGLEP ISTEKTEQAS EYVTSSEPIV 480
HREEEHAPEP IVHREEEHAP EPIVHREEEH APEPIVHREE EHAPESIVHR EEEHAPESIV 540
QREEEHAPEP ESIVHREEEH APGPVPIVHR EEEHVPELES IVHRGEEHAP EPIVHRDEGH 600
APEPIVHREE EHVPEPIVHR DEGHAPEPIV HREEEHVPEP ESIVHREEEH APEPMVLRKA 660
QLERGVETST PITDTTEPED SSLEEEIIEL DYPESPLASK ETSPSPLSPE VEHRKEPILP 720
TQMTFTPERI TLSEEEREEN ESVSTDSAFV SEYSVLQDLN HTPEKLEVEA VSVSDVKSSN 780
EPAVFSEDDE ERESYSPAMT SVSEQSLSPS TTEKTSAIQS PLFSTVSPVL SGDEASESVC 840
HSPESESAAE YSVPAHAQEL LLKTGDHKLP LKSQRVSEPI IQAEDEKEDI GLLPPAALSQ 900
AVLSEDESLG SGSFASDSKL PFKPSVSQNA TRESPQKTID DMPQFKPRGL SDPATLLEEE 960
KEAIGVGLSS SNEVSAVECA LPPQTTELLS ESHAPPPWAI SSEQVVQSEE GSRDQQRGSF 1020
SSTPELGHTS PLLLKGASSP TGLSEQGQEE DNIGPLSPDS AFASEFSFSP YPTQELEKRE 1080
LGRDSPLCLT SPSEQTVLSD EDTEEADLFS PDSASQVSIP PYRIAETEQN KVEPDELLPR 1140
RSAPDYPYFS EADEEEAGSS VVTPVPEHSE PSQEREESSP CRPVFEDLSL LPSADKTGQA 1200
ETMSDVPTIS TSVSEYLILA QQEKTQASLE PEAEDLVPPP TSGWEKRDAK SSLPAVTIAA 1260
SSSALSSVVK EETTSVLPTS QPSVSPESTC VLKPEQEPTA PLTLTSADEQ MALPRVGREK 1320
AVLDSQEATA HKSQDQTPEP RLPNVPGSGM KYSVLSDLGD EPKADVKLNL APTVTSELEQ 1380
RMLSKNEPEV AKPHSPPEET SISGPKVLSA VKTEVKQESK ITRELPAASS GRERGAEHSP 1440
PAPPALPALM EEMGKDTEAS SSATTVPVTK LDSNSTKLGR DEVLTDPSLA SPVEHPGLKG 1500
VGKSELGSGL PLPSMSTSEV LRPEPKLPVN SGVEVEREDN EPPPLQVSPT SKPTVPNDKH 1560
EEITRSPDSE NVVSDDLAPT LLALRHEMNR QAEETSSPVP GSFLSGEQEL IKLPPEPEKH 1620
KQLSEVPTAG SELIDSRDRD RSLGIEPVKP IGTEPGPSIL EKGPAELQRR GKEQEENRKL 1680
PVPASAPLET ASFDLPIEQK EPKRTLHEGQ AVEVPDESSS SADKPELGVK QLAEKKENLE 1740
QPKPFVTTER ASVTGSKVKE SLISPKDNTW MLEKPDGLVN QHEDRKPGTG QLESSESTDL 1800
MSEKLGAAPL DTDHTSETRN QETSKAPVSG EKLSQEPRRV QSKAVDDSEE GRKLASGNVE 1860
VLTQSKSVPA VKAKATPQPP ETPEVTQKPS EKSLVTEQGL PAEKGKKGIS SFKSWMSSLL 1920
FGSSIPDSKV SDNEDLETRP GPSVEKAVPA IEPKGTVPAE VNIAEKPAVH SLPEVTVKLA 1980
EEPKGVSVKS SISQDLKEKL TFLSNEDVLK QPKSNSENYG QKELPGFSEG MGESLATSVG 2040
DKHPGIHPCS PMGEKVGMEE AQNMAPLHIT ESQRRQKPEV SSPSMWNISA RKEEPSSDHK 2100
ETWLSSSDVV DRMPQKPKSA QSAFTRMNSE EPASMILPVE SKGSLSDLGE DRLRQEMPKP 2160
TSLEHCEEEV ERPTEEKDGW ETRSFSLAGK RGLAEKQEIM APLELRENEA VGELQRMPES 2220
RPFKLEESKA AERLEQRISP TEKLMEKPSK TLALDRREKE VQEWVFSEGE KQEYPPAAMP 2280
VPGASAVSLD KAQPHLLAKP TPVVEKPEHI VTEVYPEIRE RKAAETQPHP QEEGKTLVEK 2340
TKVSRVESPH GEETDGHSLT QEGNLELEKS GESRVDLKEE RRRFVMPELS LGASVAAEDG 2400
SVQPRPLSKD AARVSDMTDE TKHLGTPPTQ PSAVEPQTLV LGTSVEHTVK KQETWSDRPT 2460
VHTFQTSKDY TEEMLKQSVL ISKHHLEAVE DVHRNEPPSS AASNYTQFML SASEISADGV 2520
PPMGGTAQEP EGTSVKDEEF SVTSKPAGLS EDQKSAFSII SEGCEILNIH APAFIPSVDQ 2580
EESEQMQDKL QYLEEKASFK SISVHDEKKA AASHKTQKSK LEVPDRKITS LKENETKETH 2640
KTKEEIATDS GMGDFTPIQP TVSGEEDYFE KYTLIDYNLS PGSGKQKSTV EESSEEATKT 2700
LTSFPESSAE QALDHEYNLV KLDESFYGPE KDDSKLSHAE MQKSLAIQKP DDRNAPKGIS 2760
RDVDSRSPGM PLFDVEEGVL SKRQIFPTTP KAVNPELLEE PPALSFFYKD LYEGAGGEKN 2820
EGETASEGDS VDSETSFPRR HSDTDDGPGM YFEKYILKDD ILHDETVTQE DQGQGLEEKP 2880
VGEEDSQQLR VAEREIRRKP ETSFWEKNLE EQHKVVGREG EPTGHMETLD EAAMQQKAPI 2940
TEQVRAVTQK MSYAVPFQDT RCVLESEPSS QGNEAGNASP DVNLNVPVQE SFPEEESAAG 3000
ATYAPEVLQE RLVPSVSREE RLHNTPVQDE YDFVGSLNQE AASQAILPEE PGSESSPKEV 3060
LSQGSESFEH IREQELTSEG EPRMSASQEV WDRTEDQSAR ESVTAKTQKE PKKTQAESYC 3120
YTCKSLVSEM DKALDIHKDH EVSALDTAIS AVKVQLGEFL ENLQEKSLRI EAFVSEIESF 3180
FNTIEEKCSK NEKRLEMQNE EMMKRVLAQY DEKAQSFEEV KKKKMEFLHD QMVHFLQSMD 3240
TAKDTLETIV REAEELDETV FLASFEEINE RLLSAMESTA SLENMPAAFS LFEHYDDSSA 3300
RSDQMLKQVA VPQPPRLEPQ EPSSATSTTI AVYWSVNKED VVDSFQVYCV EEPQDDQEIN 3360
ELVEEYRLTV KESCCIFEDL EPDRCYQVWV MAVNFTGCSL PSERAIFRTA PSTAVIHVED 3420
CTVCWNTATV RWRPANPEAT ETYTLEYCRQ HSPEGEGLRS FSGIKGLQLK VNLPPNDNYF 3480
FYVRATNASG TSEQSEAALI STRGTRFLLL RETAHPALQI SANGTVISFS ERRRLTEIPS 3540
VLGEELPACG QHYWETTVAD SPAYRLGICT SSAVRAGALG QGETSWYMHC SEPQRYTFFY 3600
SGIVSEVHAT ERPARVGILL DYTNQRLLFI NAESGQLLFI VRHRFNEGVH PAFALEKPGR 3660
CTLHLGLEPP DSVRHK 3676 
Gene Ontology
 GO:0043034; C:costamere; IDA:MGI.
 GO:0070885; P:negative regulation of calcineurin-NFAT signaling cascade; IGI:MGI.
 GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IDA:MGI.
 GO:0014733; P:regulation of skeletal muscle adaptation; IGI:MGI. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR008985; ConA-like_lec_gl_sf.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR003877; SPRY_rcpt. 
Pfam
 PF00041; fn3
 PF00622; SPRY 
SMART
 SM00060; FN3 
PROSITE
 PS50188; B302_SPRY
 PS50853; FN3 
PRINTS