| Tag | Content |
|---|
| CPLM ID | CPLM-013926 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 9B |
Protein Synonyms/Alias | |
Gene Name | Tbc1d9b |
Gene Synonyms/Alias | Kiaa0676 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 546 | LVEKSLGKYSLATEE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act as a GTPase-activating protein for Rab family protein(s). |
Sequence Annotation | DOMAIN 142 209 GRAM 1.
DOMAIN 288 356 GRAM 2.
DOMAIN 509 696 Rab-GAP TBC.
DOMAIN 880 915 EF-hand.
MOD_RES 412 412 Phosphoserine (By similarity).
MOD_RES 433 433 Phosphoserine (By similarity).
MOD_RES 436 436 Phosphoserine (By similarity).
MOD_RES 464 464 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; GTPase activation; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1263 AA |
Protein Sequence | MWLGPEEVLV ANALWVTERA NPFFVLQRRR GHGKGGGLTG LLVGTLDVVL DSSARVAPYR 60
ILHQTQDSQV YWIVACGSSR KEITKHWEWL ENNLLQTLSI FDNEEDITTF VKGKIHGIIA 120
EENKNLQPQG DEDPGKFKEA ELKMRKQFGM PEGEKLVNYY SCNFWKGRVP RQGWLYLTVN 180
HLCFYSFLLG KEVSLVVQWV DVTRLEKNAT LLFPESIRVD TRDQELFFSM FLNIGETFKL 240
MEQLANLAMR QLLDSEGFLE DKALPRPIRP HKNISALKRD LDARAKNECY RATFRLPKDE 300
RLDGHTGCTL WTPFNKLHIP GQMFISNNYI CFASKEEDAC RLIIPLREVT IVEKADSSSV 360
LPSPLSISTK SKMTFLFANL KDRDFLVQRI SDFLQKTPSK QTGSSIGGTK ASVSDPAPES 420
LPTPQEASEP PASPSSPLSS PPSFSTQEIP TTSQGLLKVF QKNSPMEDLG AKGAKEKMKE 480
ESWNIHFFEY GRGMCMYRTA KTRELVLKGI PESLRGELWL LFSGAWNEMV THPGYYAELV 540
EKSLGKYSLA TEEIERDLHR SMPEHPAFQN ELGIAALRRV LTAYAFRNPT IGYCQAMNIV 600
TSVLLLYGSE EEAFWLLVAL CERMLPDYYN TRVVGALVDQ GIFEELTRDV LPRLSEKMQE 660
LGVISSISLS WFLTLFLSVM PFESAVVIVD CFFYEGIKVI LQVALAVLDA NVEQLLDCND 720
EGEAMTVLGR YLDNVVNKQS ISPPIPHLHA LLTSGDDPPV EVDIFDLLRV SYEKFSNLRA 780
DDIEQMRFKQ RLKVIQSLED TAKRSVVRAI PGDIGFSIEE LEDLYMVFKA KHLASQYWGG 840
NRSAAVHRDP SLPYLEQYRI DASQFRELFA SLTPWACGSH TPVLAGRMFR LLDQNKDSLI 900
NFKEFVTGMS GMYHGDLTEK LKALYKLHLP PALIPEEAES ALEAAHYFTE DSSSEASPLA 960
SDLDLFLPWE AQALLQEQQE GSGNEDTPER REEKGTSPPD YRHYLRMWAK EKEAQKETIK 1020
DLPKMNQEQF IELCKTLYNM FSEDPMEQDL YHAIATVASL LLRIGEVGKK FSALTTKKPR 1080
DGAHSGDPNS ATEEDEPPTP KLHQDPTQEC QPPAAGDRQA KASGDMHLGK ALQDSHVIVE 1140
GGSGEGQGSP SLLLSDDETK DDMSMSSYSV VSTGSLQCED LTEDTVLVGG GACSPTATSR 1200
AGGTVDTDWC ISFEQILASI LTESVLVNFF EKRVDIGLKI KDQKKVERQF STSSDHEPPG 1260
VLG 1263 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005622; C:intracellular; IEA:InterPro. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |