CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033871
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Insulin-like growth factor-binding protein 2 
Protein Synonyms/Alias
  
Gene Name
 Igfbp2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
20KPLKSGMKELAVFREubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 158 AA 
Protein Sequence
MNMLGGGSSA GRKPLKSGMK ELAVFREKVN EQHRQMGKGA KHLSLEEPKK LRPPPARTPC 60
QQELDQVLER ISTMRLPDDR GPLEHLYSLH IPNCDKHGRY NLKQCKMSLN GQRGECWCVN 120
PNTGKPIQGA PTIRGDPECH LFYNEQQETG GAHAQSVQ 158 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
 GO:0005615; C:extracellular space; IDA:MGI.
 GO:0007568; P:aging; IEA:Compara.
 GO:0032870; P:cellular response to hormone stimulus; IEA:Compara.
 GO:0007565; P:female pregnancy; IEA:Compara.
 GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0032355; P:response to estradiol stimulus; IEA:Compara.
 GO:0051384; P:response to glucocorticoid stimulus; IEA:Compara.
 GO:0010226; P:response to lithium ion; IEA:Compara.
 GO:0009612; P:response to mechanical stimulus; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara.
 GO:0032526; P:response to retinoic acid; IEA:Compara.
 GO:0006950; P:response to stress; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:Compara. 
Interpro
 IPR012210; IGFBP-2.
 IPR009168; IGFBP1-6.
 IPR022321; IGFBP_1-6_chordata.
 IPR000716; Thyroglobulin_1. 
Pfam
 PF00086; Thyroglobulin_1 
SMART
 SM00211; TY 
PROSITE
 PS00484; THYROGLOBULIN_1_1
 PS51162; THYROGLOBULIN_1_2 
PRINTS
 PR01976; IGFBPFAMILY.
 PR01978; IGFBPFAMILY2.