| Tag | Content |
|---|
| CPLM ID | CPLM-004757 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Respiratory nitrate reductase 2 alpha chain |
Protein Synonyms/Alias | |
Gene Name | narZ |
Gene Synonyms/Alias | b1468; JW1463 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 110 | LYSANRLKYPLIRKR | acetylation | [1] | | 637 | SPLADASKYSGHLID | acetylation | [1] | | 674 | GIKAEADKAGLSPTE | acetylation | [1] | | 908 | SLGPLMDKLGNGGKG | acetylation | [1] | | 1228 | FIMIRKMKNVNWLDD | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | This is a second nitrate reductase enzyme which can substitute for the NRA enzyme and allows E.coli to use nitrate as an electron acceptor during anaerobic growth. |
Sequence Annotation | DOMAIN 43 107 4Fe-4S Mo/W bis-MGD-type.
METAL 50 50 Iron-sulfur (4Fe-4S); via pros nitrogen
METAL 54 54 Iron-sulfur (4Fe-4S) (By similarity).
METAL 58 58 Iron-sulfur (4Fe-4S) (By similarity).
METAL 93 93 Iron-sulfur (4Fe-4S) (By similarity).
METAL 223 223 Molybdenum (By similarity). |
Keyword | 4Fe-4S; Cell membrane; Complete proteome; Direct protein sequencing; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Molybdenum; Nitrate assimilation; Oxidoreductase; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1246 AA |
Protein Sequence | MSKLLDRFRY FKQKGETFAD GHGQVMHSNR DWEDSYRQRW QFDKIVRSTH GVNCTGSCSW 60
KIYVKNGLVT WEIQQTDYPR TRPDLPNHEP RGCPRGASYS WYLYSANRLK YPLIRKRLIE 120
LWREALKQHS DPVLAWASIM NDPQKCLSYK QVRGRGGFIR SNWQELNQLI AAANVWTIKT 180
YGPDRVAGFS PIPAMSMVSY AAGTRYLSLL GGTCLSFYDW YCDLPPASPM TWGEQTDVPE 240
SADWYNSSYI IAWGSNVPQT RTPDAHFFTE VRYKGTKTIA ITPDYSEVAK LCDQWLAPKQ 300
GTDSALAMAM GHVILKEFHL DNPSDYFINY CRRYSDMPML VMLEPRDDGS YVPGRMIRAS 360
DLVDGLGESN NPQWKTVAVN TAGELVVPNG SIGFRWGEKG KWNLESIAAG TETELSLTLL 420
GQHDAVAGVA FPYFGGIENP HFRSVKHNPV LVRQLPVKNL TLVDGNTCPV VSVYDLVLAN 480
YGLDRGLEDE NSAKDYAEIK PYTPAWGEQI TGVPRQYIET IAREFADTAH KTHGRSMIIL 540
GAGVNHWYHM DMNYRGMINM LIFCGCVGQS GGGWAHYVGQ EKLRPQTGWL PLAFALDWNR 600
PPRQMNSTSF FYNHSSQWRY EKVSAQELLS PLADASKYSG HLIDFNVRAE RMGWLPSAPQ 660
LGRNPLGIKA EADKAGLSPT EFTAQALKSG DLRMACEQPD SSSNHPRNLF VWRSNLLGSS 720
GKGHEYMQKY LLGTESGIQG EELGASDGIK PEEVEWQTAA IEGKLDLLVT LDFRMSSTCL 780
FSDIVLPTAT WYEKDDMNTS DMHPFIHPLS AAVDPAWESR SDWEIYKGIA KAFSQVCVGH 840
LGKETDVVLQ PLLHDSPAEL SQPCEVLDWR KGECDLIPGK TAPNIVAVER DYPATYERFT 900
SLGPLMDKLG NGGKGISWNT QDEIDFLGKL NYTKRDGPAQ GRPLIDTAID ASEVILALAP 960
ETNGHVAVKA WQALGEITGR EHTHLALHKE DEKIRFRDIQ AQPRKIISSP TWSGLESDHV 1020
SYNAGYTNVH ELIPWRTLSG RQQLYQDHPW MRAFGESLVA YRPPIDTRSV SEMRQIPPNG 1080
FPEKALNFLT PHQKWGIHST YSENLLMLTL SRGGPIVWIS ETDARELTIV DNDWVEVFNA 1140
NGALTARAVV SQRVPPGMTM MYHAQERIMN IPGSEVTGMR GGIHNSVTRV CPKPTHMIGG 1200
YAQLAWGFNY YGTVGSNRDE FIMIRKMKNV NWLDDEGRDQ VQEAKK 1246 |
Gene Ontology | GO:0016020; C:membrane; IDA:UniProtKB. GO:0009325; C:nitrate reductase complex; IEA:InterPro. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0051539; F:4 iron, 4 sulfur cluster binding; IPI:EcoCyc. GO:0009055; F:electron carrier activity; IDA:EcoCyc. GO:0005506; F:iron ion binding; IPI:EcoCyc. GO:0030151; F:molybdenum ion binding; IDA:EcoCyc. GO:0008940; F:nitrate reductase activity; IEA:EC. GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IBA:RefGenome. GO:0009061; P:anaerobic respiration; IDA:EcoCyc. GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |