UniProt Accession

 AUGN_RAT; D4A540 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 Augurin 

Protein Synonyms/Alias

 Esophageal cancer-related gene 4 protein homolog 

Gene Name

 Ecrg4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
66	KEFLGGLKRAKRQLW	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. 

Sequence Annotation

  

Keyword

 Cleavage on pair of basic residues; Complete proteome; Cytoplasmic vesicle; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 148 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
 GO:0090398; P:cellular senescence; IEA:Compara.
 GO:0008054; P:cyclin catabolic process; IEA:Compara.
 GO:0070314; P:G1 to G0 transition; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS