UniProt Accession

 IF1A_MOUSE; Q60872; O88847; Q8R2M4; Q9CX76; Q9DB61 

Genbank Protein ID

 AF026481; AK009026; AK013268; AK019451; BC027437; U28419 

Genbank Nucleotide ID

 AAC63934.1; BAB26034.1; BAB28759.1; BAB31727.1; AAH27437.1; AAB05664.1 

Protein Name

 Eukaryotic translation initiation factor 1A 

Protein Synonyms/Alias

 eIF-1A; Eukaryotic translation initiation factor 4C; eIF-4C 

Gene Name

 Eif1a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
29	EKRELVFKEDGQEYA	acetylation	[1]
94	NKADVILKYNADEAR	acetylation	[1]
94	NKADVILKYNADEAR	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. 

Sequence Annotation

 DOMAIN 22 96 S1-like.  

Keyword

 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 144 AA 

Protein Sequence

Gene Ontology

 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR006196; RNA-binding_domain_S1_IF1.
 IPR001253; TIF_eIF-1A.
 IPR018104; TIF_eIF-1A_CS. 

Pfam

 PF01176; eIF-1a 

SMART

 SM00652; eIF1a 

PROSITE

 PS01262; IF1A
 PS50832; S1_IF1_TYPE 

PRINTS