CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038887
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein LOC100909666 
Protein Synonyms/Alias
  
Gene Name
 LOC100909666 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
90LRLEVPLKDVRSCGLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1549 AA 
Protein Sequence
MRLLWGLAWA FSFFASSLQK PRLLLFSPSV VNLGTPLSVG VQLLDAPAGQ EVKGSVYLRN 60
PTSGPCSPKK DFKLSSGNDF VLLRLEVPLK DVRSCGLFGL RRAPHIQLVA HSPWLKNTAS 120
KATETQGVNL LFSSRRGHIF VQTDQPIYNP GQRVRYRVFA LDQKMRPSTD TLTVTVENSH 180
GLRVRKKEVF APTSIFQDDF IIPDISEPGT WKISARFSDG LESNRSTHFE VKKYVLPNFE 240
VKLTPWKPYI LTVPSYREEI QLDVQARYVY GKPVQGVAYT RFALMDEQGK KSFLRGLETQ 300
TKLVEGQTHI SISRDQFQAA LGKVNTEIGD LEGLRLYAAV AVIESPGGEM EEAELTSWPF 360
VSSAFSLDLS HTKQHLVPGA PFLLQALVRE MSGSEASDVP VKVSATLLSG SDSKVLDFQQ 420
NTNGIGQVSF SIHVPPTITE LRLLVSAGSL YPAVAKLTVQ APPSRGPGFL SIEPLDLRSP 480
RVGDTFVLSL RTVGIPMPTF SHYYYMIISR GQIMAMSREP RRALTSISVL VDHHLAPSFY 540
FVAYFYHQGL PVANSLLINV QPGDCEGKLE LKVDGAKEYR NGDSMKLQLQ TDSEALVALG 600
AVDTALYAVG GRSHKPLDMS KVFEVMNSYN LGCGPGGGDD ALQVFQTAGL AFSDGDRLTQ 660
TKENLSCPKE KKSRQKRNVN FQKAISEKLG QYSSPDTKRC CQDGMTKLPM ARTCEQRAAR 720
VPQPACREPF LSCCKFAEDL RRNQTRSQAG LARAQDMLQE EDLIDEDDIL VRSFFPENWL 780
WRVEPVDRSK LLTVWLPDSL TTWEIHGVSL SKSKGLCVAK PTRVRVFREF HLHLRLPISV 840
RRFEQLELRP VLYNYLSEDV TVSVHVSPVE GLCLAGGGLL AQQVSVPAGS ARPVAFSVVP 900
TAAASIPLKV VARGSFTIGD AVSKILQIEK EGAIHREEIV YNLDPLNNLG RSLEIPGSSD 960
PNVIPDGDFS SFVRVTASEP LETLGSEGAL SPGGVASLLR LPRGCAEQTM IYLAPTLTAS 1020
HYLDRTEQWS KLPPETKDHA VDLIQKGHMR IQQFRKKDGS FGAWLHRDSS TWLTAFVLKI 1080
LSLAQEQIGD SPEKLQETAG WLLGQQLDDG SFHDPCPVIH RGMQGGLVGT DETVALTAFV 1140
VIALHHGLAV FQDENSQQLK KRVEASITKA NSFLGQKASA GLLGAHASAI TAYALTLTKA 1200
SEDLRNVAHN SLMAMAEETG ENLYWGSAIG SQDNVVSSTP APRNPSEPVP QAPALWIETT 1260
AYGLLHLLLR EGKGEMADKV ATWLTHQGSF QGGFRSTQDT VVTLDALSAY WIASHTTEEK 1320
ALNVTLSSMG RNGYKSHLLQ LNNHQVKGLE EELKFSLGST INVKVGGNSK GTLKILRTYN 1380
VLDMKNTTCQ DLRIEVTVTG YVEYTREANE DYEYDYDMPA ADDPSVHSQP VTPLQLFEGR 1440
RSRRRREAPK AADEQESRVQ YTVCIWRNGN LGLSGMAIAD ITLLSGFQAL RADLEKLTSL 1500
SDRYVSHFET DGPHVLLYFD SVPTTRECVG FGALQEVAVG LVQPASAVL 1549 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:InterPro.
 GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
 GO:0006956; P:complement activation; IEA:InterPro.
 GO:0006954; P:inflammatory response; IEA:InterPro.
 GO:0010951; P:negative regulation of endopeptidase activity; IEA:GOC. 
Interpro
 IPR009048; A-macroglobulin_rcpt-bd.
 IPR011626; A2M_comp.
 IPR002890; A2M_N.
 IPR011625; A2M_N_2.
 IPR000020; Anaphylatoxin/fibulin.
 IPR018081; Anaphylatoxin_.
 IPR001840; Anaphylatoxn.
 IPR001599; Macroglobln_a2.
 IPR019742; MacrogloblnA2_CS.
 IPR019565; MacrogloblnA2_thiol-ester-bond.
 IPR008930; Terpenoid_cyclase/PrenylTrfase. 
Pfam
 PF00207; A2M
 PF07678; A2M_comp
 PF01835; A2M_N
 PF07703; A2M_N_2
 PF07677; A2M_recep
 PF01821; ANATO
 PF10569; Thiol-ester_cl 
SMART
 SM00104; ANATO 
PROSITE
 PS00477; ALPHA_2_MACROGLOBULIN
 PS01177; ANAPHYLATOXIN_1
 PS01178; ANAPHYLATOXIN_2 
PRINTS
 PR00004; ANAPHYLATOXN.