CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033875
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microsomal glutathione S-transferase 1 
Protein Synonyms/Alias
  
Gene Name
 Mgst1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
42AFQRITNKVFANPEDacetylation[1, 2, 3]
42AFQRITNKVFANPEDubiquitination[4]
55EDCAGFGKGENAKKFacetylation[1, 2, 3]
55EDCAGFGKGENAKKFubiquitination[4]
60FGKGENAKKFVRTDEacetylation[2, 3]
60FGKGENAKKFVRTDEubiquitination[4]
68KFVRTDEKVERVRRLacetylation[2, 3]
Reference
 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 102 AA 
Protein Sequence
MADLRQLMDN EVLMAFTSYA TIILTKMMFM SSATAFQRIT NKVFANPEDC AGFGKGENAK 60
KFVRTDEKVE RVRRLSSSFF LHQFKTCCYF HNQMAGPDCG YT 102 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0004364; F:glutathione transferase activity; IDA:MGI.
 GO:0006749; P:glutathione metabolic process; IDA:MGI. 
Interpro
 IPR023352; MAPEG-like_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS