| Tag | Content |
|---|
| CPLM ID | CPLM-014541 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Carnitine O-palmitoyltransferase 1, muscle isoform |
Protein Synonyms/Alias | CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein |
Gene Name | Cpt1b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 214 | LAKEFQDKIAPRLQK | acetylation | [1] | | 766 | LDIADLFKISKTDS* | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | |
Sequence Annotation | REGION 555 567 Coenzyme A binding (By similarity).
ACT_SITE 473 473 Proton acceptor (By similarity).
BINDING 589 589 Carnitine (By similarity).
BINDING 602 602 Carnitine (By similarity). |
Keyword | Acyltransferase; Complete proteome; Fatty acid metabolism; Lipid metabolism; Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 772 AA |
Protein Sequence | MAEAHQAVAF QFTVTPDGVD FRLSREALRH IYLSGINSWK KRLIRIKNGI LRGVYPGSPT 60
SWLVVVMATV GSNYCKVDIS MGLVHCIQRC LPTRYGSYGT PQTETLLSMV IFSTGVWATG 120
IFLFRQTLKL LLSYHGWMFE MHSKTSHATK IWAICVRLLS SRRPMLYSFQ TSLPKLPVPS 180
VPATIHRYLD SVRPLLDDEA YFRMESLAKE FQDKIAPRLQ KYLVLKSWWA TNYVSDWWEE 240
YVYLRGRSPI MVNSNYYAMD FVLIKNTSQQ AARLGNTVHA MIMYRRKLDR EEIKPVMALG 300
MVPMCSYQME RMFNTTRIPG KETDLLQHLS ESRHVAVYHK GRFFKVWLYE GSCLLKPRDL 360
EMQFQRILDD TSPPQPGEEK LAALTAGGRV EWAEARQKFF SSGKNKMSLD TIERAAFFVA 420
LDEDSHCYNP DDEASLSLYG KSLLHGNCYN RWFDKSFTLI SCKNGQLGLN TEHSWADAPI 480
IGHLWEFVLA TDTFHLGYTE TGHCVGEPNT KLPPPQRMQW DIPEQCQTAI ENSYQVAKAL 540
ADDVELYCFQ FLPFGKGLIK KCRTSPDAFV QIALQLAHFR DKGKFCLTYE ASMTRMFREG 600
RTETVRSCTS ESTAFVRAMM TGSHKKQDLQ DLFRKASEKH QNMYRLAMTG AGIDRHLFCL 660
YIVSKYLGVR SPFLDEVLSE PWSLSTSQIP QFQICMFDPK QYPNHLGAGG GFGPVADHGY 720
GVSYMIAGEN TMFFHVSSKL SSSETNALRF GNHIRQALLD IADLFKISKT DS 772 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:RGD. GO:0004095; F:carnitine O-palmitoyltransferase activity; IDA:RGD. GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway. GO:0015909; P:long-chain fatty acid transport; IDA:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |