CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033913
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein S100-A4 
Protein Synonyms/Alias
  
Gene Name
 S100a4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
18VIVSTFHKYSGKEGDacetylation[1]
22TFHKYSGKEGDKFKLacetylation[2]
26YSGKEGDKFKLNKTEacetylation[2]
31GDKFKLNKTELKELLacetylation[2]
35KLNKTELKELLTRELacetylation[1, 2]
57TDEAAFQKVMSNLDSacetylation[1, 2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Metal-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 101 AA 
Protein Sequence
MARPLEEALD VIVSTFHKYS GKEGDKFKLN KTELKELLTR ELPSFLGERT DEAAFQKVMS 60
NLDSNRDNEV DFQEYCVFLS CIAMMCNEFF EGCPDKEPRK K 101 
Gene Ontology
 GO:0005509; F:calcium ion binding; IDA:MGI. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001751; S100/CaBP-9k_CS.
 IPR013787; S100_Ca-bd_sub. 
Pfam
 PF01023; S_100 
SMART
  
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00303; S100_CABP 
PRINTS