CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018243
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 THAP domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 THAP3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
197KKLFLTLKENEKLRKubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. 
Sequence Annotation
 ZN_FING 1 82 THAP-type.
 MOTIF 177 180 HCFC1-binding motif (HBM).  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 239 AA 
Protein Sequence
MPKSCAARQC CNRYSSRRKQ LTFHRFPFSR PELLKEWVLN IGRGNFKPKQ HTVICSEHFR 60
PECFSAFGNR KNLKHNAVPT VFAFQDPTQQ VRENTDPASE RGNASSSQKE KVLPEAGAGE 120
DSPGRNMDTA LEELQLPPNA EGHVKQVSPR RPQATEAVGR PTGPAGLRRT PNKQPSDHSY 180
ALLDLDSLKK KLFLTLKENE KLRKRLQAQR LVMRRMSSRL RACKGHQGLQ ARLGPEQQS 239 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR026520; THAP3.
 IPR006612; Znf_C2CH. 
Pfam
 PF05485; THAP 
SMART
 SM00692; DM3
 SM00980; THAP 
PROSITE
 PS50950; ZF_THAP 
PRINTS