CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038098
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Netrin receptor UNC5C 
Protein Synonyms/Alias
  
Gene Name
 Unc5c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
374GFQPVNIKAARQDLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 876 AA 
Protein Sequence
MRKGLRATAA RCGLGLGYLL QMLVLPALAL LSASGTGSAA QGLIVREVSI EISRQQVEEL 60
FGPEDYWCQC VAWSSAGTTK SRKAYVRIAY LRKTFEQEPL GKEVSLEQEV LLQCRPPEGI 120
PVAEVEWLKN EDIIDPAEDR NFYITIDHNL IIKQARLSDT ANYTCVAKNI VAKRKSTTAT 180
VIVYVNGGWS TWTEWSVCNS RCGRGYQKRT RTCTNPAPLN GGAFCEGQSV QKIACTTLCP 240
VDGRWTSWSK WSTCGTECTH WRRRECTAPA PKNGGKDCDG LVLQSKNCTD GLCMQGFIYP 300
ISTEHRPQNE YGFSSAPDSD DVALYVGIVI AVTVCLAITV VVALFVYRKN HRDFESDIID 360
SSALNGGFQP VNIKAARQDL LAVPPDLTSA AAMYRGPVYA LHDVSDKIPM TNSPILDPLP 420
NLKIKVYNSS GAVTPQDDLA EFSSKLSPQM TQSLLENEAL NLKNQSLARQ TDPSCTAFGT 480
FNSLGGHLII PNSGVSLLIP AGAIPQGRVY EMYVTVHRKE NMRPPMEDSQ TLLTPVVSCG 540
PPGALLTRPV ILTLHHCADP STEDWKIQLK NQAVQGQWED VVVVGEENFT TPCYIQLDAE 600
ACHILTENLS TYALVGQSTT KAAAKRLKLA IFGPLCCSSL EYSIRVYCLD DTQDALKEVL 660
QLERQMGGQL LEEPKALHFK GSIHNLRLSI HDIAHSLWKS KLLAKYQEIP FYHIWSGSQR 720
NLHCTFTLER LSLNTVELVC KLCVRQVEGE GQIFQLNCTV SEEPTGIDLP LLDPASTITT 780
VTGPSAFSIP LPIRQKLCSS LDAPQTRGHD WRMLAHKLNL DRYLNYFATK SSPTGVILDL 840
WEAQNFPDGN LSMLAAVLEE MGRHETVVSL AAEGQY 876 
Gene Ontology
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0005042; F:netrin receptor activity; IDA:MGI.
 GO:0033564; P:anterior/posterior axon guidance; IMP:MGI.
 GO:0007420; P:brain development; IMP:MGI.
 GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.
 GO:0030334; P:regulation of cell migration; IMP:MGI. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR000884; Thrombospondin_1_rpt.
 IPR000906; ZU5. 
Pfam
 PF00531; Death
 PF07679; I-set
 PF00090; TSP_1
 PF00791; ZU5 
SMART
 SM00005; DEATH
 SM00408; IGc2
 SM00209; TSP1
 SM00218; ZU5 
PROSITE
 PS50835; IG_LIKE
 PS50092; TSP1
 PS51145; ZU5 
PRINTS