CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009148
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neuron-specific vesicular protein calcyon 
Protein Synonyms/Alias
  
Gene Name
 Caly 
Gene Synonyms/Alias
 Drd1ip 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
63LTSADQPKKFADLEGubiquitination[1]
64TSADQPKKFADLEGQubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. 
Sequence Annotation
  
Keyword
 Cell membrane; Complete proteome; Cytoplasmic vesicle; Endocytosis; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 226 AA 
Protein Sequence
MVKLGCSFSG KPGKETGDQD GAAMDSVPLI SPLDVSQLQP SFPDQVVIKT QTEYQLTSAD 60
QPKKFADLEG QRLACSHPEE GRRLPTARMI AFAMALLGCV LIMYKAIWYD QFTCPDGFLL 120
RHKICTPLTL EMYYTEMDPE RHRSILAAIG AYPLSRKHGT EMPAIWGNSY RAGKEEHKGT 180
TPAAMTVSTA AAAAAAEGNE PSGKPLDMRE KEDPQKAEDV PSQSPK 226 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.
 GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
 GO:0032051; F:clathrin light chain binding; ISS:UniProtKB.
 GO:0050780; F:dopamine receptor binding; TAS:RGD.
 GO:0048268; P:clathrin coat assembly; ISS:UniProtKB.
 GO:0007212; P:dopamine receptor signaling pathway; IEA:InterPro.
 GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
 GO:0045807; P:positive regulation of endocytosis; ISS:UniProtKB. 
Interpro
 IPR009431; calcyon_neuron-sp. 
Pfam
 PF06387; Calcyon 
SMART
  
PROSITE
  
PRINTS