CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017657
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein ZNF738 
Protein Synonyms/Alias
  
Gene Name
 ZNF738 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
12RYGVYPVKGASGYPGubiquitination[1, 2]
32LEYSYFEKGPLTFRDubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 35 106 KRAB.  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 137 AA 
Protein Sequence
MDDLRYGVYP VKGASGYPGA ERNLLEYSYF EKGPLTFRDV VIEFSQEEWQ CLDTAQQDLY 60
RKVMLENFRN LVFLGIDVSK PDLITCLEQG KDPWNMKRHS MVATPPESGV LKFPTIIILL 120
SRCFFQSVNI CFIYLEP 137 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
 GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
 GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR026613; KRAB_dom_C2H2_Znf_fam.
 IPR001909; Krueppel-associated_box. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB 
PROSITE
 PS50805; KRAB 
PRINTS