CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016026
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaphilin 
Protein Synonyms/Alias
  
Gene Name
 Snph 
Gene Synonyms/Alias
 Kiaa0374 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
111DTEIDDLKTQLSRMQubiquitination[1]
153KQVIDTVKNNLIDKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Inhibits SNARE complex formation by absorbing free syntaxin-1 (By similarity). 
Sequence Annotation
 MOD_RES 20 20 Phosphoserine.
 MOD_RES 293 293 Phosphotyrosine.  
Keyword
 Alternative splicing; Cell junction; Coiled coil; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Synapse; Synaptosome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 495 AA 
Protein Sequence
MAMSLQGSRR ASAGSRRRTS PPVSVRDAYG TSSLSSSSNS GSCKGSDSSP TPRRSMKYTL 60
CSDNHGIKPP TPEQYLTPLQ QKEVCIRHLK ARLKDTQDRL QDRDTEIDDL KTQLSRMQED 120
WIEEECHRVE AQLALKEARK EIRQLKQVID TVKNNLIDKD KGLQKYFVDI NIQNKKLETL 180
LHSMEVAQNG VAKEEGTGES AGGSPARSLT RSSTYTKLSD PAVCGDRQPG DPSNTSAEDG 240
ADSGYVAADD TLSRTDALEA SSLLSSGVDC GLEEASLHSS FNLGPRFPAS NTYEKLLCGM 300
EAGVQVSCMQ ERAIQTDFVQ YQPDLNTILE KVGQAQVCGS VLKDRHSELD PHPSGPRDPD 360
SAVVVTVGDE LEAPEPITCG PATHRPAVNS NPGLPVSVVC PVEEEEEEAA AATTTEKEPK 420
SYWSRHYIVD LLAVVVPAVP TVAWLCRSQR RQGQPIYNIS SLLRGCCTVA LHSIRRISCR 480
SLGQPSSSTA GGSQL 495 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005881; C:cytoplasmic microtubule; ISS:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031966; C:mitochondrial membrane; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0042734; C:presynaptic membrane; IEA:Compara.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0030182; P:neuron differentiation; IEA:Compara. 
Interpro
 IPR026196; Syntaphilin. 
Pfam
  
SMART
  
PROSITE
  
PRINTS