UniProt Accession

 GBG7_HUMAN; O60262; B2R496 

Genbank Protein ID

 AB010414; AF493874; AK311750; AC005512; BC014466; BC053630 

Genbank Nucleotide ID

 BAA28348.1; AAM12588.1; BAG34693.1; AAC32595.1; AAH14466.1; AAH53630.1 

Protein Name

 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 

Protein Synonyms/Alias

  

Gene Name

 GNG7 

Gene Synonyms/Alias

 GNGT7 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
30	IERIKVSKAASDLMS	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.
 MOD_RES 65 65 Cysteine methyl ester (By similarity).
 LIPID 65 65 S-geranylgeranyl cysteine (By  

Keyword

 Acetylation; Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Prenylation; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 68 AA 

Protein Sequence

Gene Ontology

 GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0001662; P:behavioral fear response; IEA:Compara.
 GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
 GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0007626; P:locomotory behavior; IEA:Compara.
 GO:0007168; P:receptor guanylyl cyclase signaling pathway; IEA:Compara.
 GO:0045761; P:regulation of adenylate cyclase activity; IEA:Compara.
 GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
 GO:0044281; P:small molecule metabolic process; TAS:Reactome.
 GO:0007268; P:synaptic transmission; TAS:Reactome. 

Interpro

 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 

Pfam

 PF00631; G-gamma 

SMART

 SM00224; GGL 

PROSITE

 PS50058; G_PROTEIN_GAMMA 

PRINTS

 PR00321; GPROTEING.